4-(Trifluoromethoxy)aniline

Name: 4-(Trifluoromethoxy)aniline
Brand: Vaqora Chemicals
SKU: VQ-027822

About 4-(Trifluoromethoxy)aniline

4-(Trifluoromethoxy)aniline (CAS 461-82-5) is an impurity of Riluzole offered by Vaqora Chemicals. Formula C7H6F3NO, molecular weight 177.12 g/mol. Common synonyms include 4-(Trifluoromethoxy)benzenamine and 4-TFMeA.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 9 hazard statements. Review the Safety Data Sheet before use.

This Riluzole impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 4-(Trifluoromethoxy)aniline in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Riluzole

View every impurity, metabolite and intermediate we list for Riluzole.

Riluzole impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Trifluoromethoxy)aniline
Catalogue No.	VQ-027822
CAS Number	461-82-5
IUPAC name	4-(trifluoromethoxy)aniline
Molecular formula	C₇H₆F₃NO
Molecular weight	177.12 g/mol
Exact mass	177.0401
Grade	Reference Standard
HSN code	38229090
InChIKey	XUJFOSLZQITUOI-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1N)OC(F)(F)F
PubChem CID	600848

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 5
TPSA	35.3 Å²
Synonyms	4-(Trifluoromethoxy)benzenamine, 4-TFMeA, Benzenamine, 4-(trifluoromethoxy)-, p-Trifluoromethoxyaniline, 4-trifluoromethoxy-phenylamine, 4-trifluoromethoxyphenylamine, p-aminotrifluoromethoxybenzene, p-Aminophenyl trifluoromethyl ether, 4-(trifluoromethoxy)phenylamine, 4-trifluoromethoxyanilin

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H310Fatal in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H330Fatal if inhaled
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P262, P264, P264 + P265, P270, P271, P273, P280, P284, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P319, P320, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Trifluoromethoxy)aniline?

The CAS Registry Number of 4-(Trifluoromethoxy)aniline is 461-82-5. It is also known as 4-(Trifluoromethoxy)benzenamine, 4-TFMeA, Benzenamine, 4-(trifluoromethoxy)-.

What is the molecular formula and molecular weight of 4-(Trifluoromethoxy)aniline?

4-(Trifluoromethoxy)aniline has the molecular formula C7H6F3NO and a molecular weight of 177.12 g/mol. Its IUPAC name is 4-(trifluoromethoxy)aniline.

What is 4-(Trifluoromethoxy)aniline used for?

4-(Trifluoromethoxy)aniline is supplied as a characterised reference material related to Riluzole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Trifluoromethoxy)aniline can I order?

We supply 4-(Trifluoromethoxy)aniline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Trifluoromethoxy)aniline?

Yes. Every lot of 4-(Trifluoromethoxy)aniline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Trifluoromethoxy)aniline be shipped internationally?

Yes. 4-(Trifluoromethoxy)aniline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.