4-(Trifluoromethyl)benzonitrile

Name: 4-(Trifluoromethyl)benzonitrile
Brand: Vaqora Chemicals
SKU: VQ-050248

About 4-(Trifluoromethyl)benzonitrile

Listed under CAS 455-18-5, 4-(Trifluoromethyl)benzonitrile is a process intermediate or related compound of Benserazide available from Vaqora Chemicals. Its molecular formula is C8H4F3N and its molecular weight is 171.12 g/mol. Alternative names: Benzonitrile, 4-(trifluoromethyl)- and p-Cyanobenzotrifluoride.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Benserazide, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 4-(Trifluoromethyl)benzonitrile in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Benserazide

View every impurity, metabolite and intermediate we list for Benserazide.

Benserazide impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Trifluoromethyl)benzonitrile
Catalogue No.	VQ-050248
CAS Number	455-18-5
IUPAC name	4-(trifluoromethyl)benzonitrile
Molecular formula	C₈H₄F₃N
Molecular weight	171.12 g/mol
Exact mass	171.0296
HSN code	2933
InChIKey	DRNJIKRLQJRKMM-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C#N)C(F)(F)F
PubChem CID	67995

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	0 / 4
TPSA	23.8 Å²
Synonyms	Benzonitrile, 4-(trifluoromethyl)-, p-Cyanobenzotrifluoride, 4-Trifluoromethylbenzoic acid nitrile, .alpha.,.alpha.,.alpha.-Trifluoro-p-toluonitrile, alpha,alpha,alpha-Trifluoro-p-toluonitrile, alpha,alpha,alpha-Trifluoro-p-tolunitrile, p-(Trifluoromethyl)benzonitrile, p-TRIFLUOROMETHYLBENZONITRILE, Benzonitrile, p-(trifluoromethyl)-, 4-Cyanobenzotrifluoride, alpha,alpha,alpha-Trifluoro-4-toluonitrile

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Signal word: Danger

Hazard statements

H228Flammable solid
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary statements: P210, P240, P241, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Trifluoromethyl)benzonitrile?

The CAS Registry Number of 4-(Trifluoromethyl)benzonitrile is 455-18-5. It is also known as Benzonitrile, 4-(trifluoromethyl)-, p-Cyanobenzotrifluoride, 4-Trifluoromethylbenzoic acid nitrile.

What is the molecular formula and molecular weight of 4-(Trifluoromethyl)benzonitrile?

4-(Trifluoromethyl)benzonitrile has the molecular formula C8H4F3N and a molecular weight of 171.12 g/mol. Its IUPAC name is 4-(trifluoromethyl)benzonitrile.

What is 4-(Trifluoromethyl)benzonitrile used for?

4-(Trifluoromethyl)benzonitrile is supplied as a characterised reference material related to Benserazide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Trifluoromethyl)benzonitrile can I order?

We supply 4-(Trifluoromethyl)benzonitrile, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Trifluoromethyl)benzonitrile?

Yes. Every lot of 4-(Trifluoromethyl)benzonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Trifluoromethyl)benzonitrile be shipped internationally?

Yes. 4-(Trifluoromethyl)benzonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.