4,4′-Bis(bromomethyl)biphenyl

Name: 4,4′-Bis(bromomethyl)biphenyl
Brand: Vaqora Chemicals
SKU: VQ-032566

About 4,4′-Bis(bromomethyl)biphenyl

4,4′-Bis(bromomethyl)biphenyl (CAS 20248-86-6) is an impurity of Valsartan offered by Vaqora Chemicals. The compound has the formula C14H12Br2, corresponding to a molecular weight of 340.05 g/mol. Its systematic (IUPAC) name is 1-(bromomethyl)-4-[4-(bromomethyl)phenyl]benzene. Alternative names: 4,4'-Bis(bromomethyl)-1,1'-biphenyl and 1,1'-Biphenyl, 4,4'-bis(bromomethyl)-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Valsartan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4,4′-Bis(bromomethyl)biphenyl in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	4,4′-Bis(bromomethyl)biphenyl
Catalogue No.	VQ-032566
CAS Number	20248-86-6
IUPAC name	1-(bromomethyl)-4-[4-(bromomethyl)phenyl]benzene
Molecular formula	C₁₄H₁₂Br₂
Molecular weight	340.05 g/mol
Exact mass	339.9285
Grade	Reference Standard
HSN code	38229090
InChIKey	HMUGRILXVBKBID-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1CBr)C2=CC=C(C=C2)CBr
PubChem CID	621238

Physical properties
Physical form	Solid
LogP (XLogP3)	5.5
H-bond donors / acceptors	0 / 0
TPSA	0 Å²
Synonyms	4,4'-Bis(bromomethyl)-1,1'-biphenyl, 1,1'-Biphenyl, 4,4'-bis(bromomethyl)-, 4,4 inverted exclamation mark -Bis(bromomethyl)biphenyl, alpha,alpha'-Dibromo-p,p'-ditolyl, 4,4'-Bis(bromomethyl)-1,1'biphenyl, 4,4'-(Bisbromomethyl)-1,1'-biphenyl

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P264, P270, P273, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P330, P363, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,4′-Bis(bromomethyl)biphenyl?

The CAS Registry Number of 4,4′-Bis(bromomethyl)biphenyl is 20248-86-6. It is also known as 4,4'-Bis(bromomethyl)-1,1'-biphenyl, 1,1'-Biphenyl, 4,4'-bis(bromomethyl)-, 4,4 inverted exclamation mark -Bis(bromomethyl)biphenyl.

What is the molecular formula and molecular weight of 4,4′-Bis(bromomethyl)biphenyl?

4,4′-Bis(bromomethyl)biphenyl has the molecular formula C14H12Br2 and a molecular weight of 340.05 g/mol. Its IUPAC name is 1-(bromomethyl)-4-[4-(bromomethyl)phenyl]benzene.

What is 4,4′-Bis(bromomethyl)biphenyl used for?

4,4′-Bis(bromomethyl)biphenyl is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,4′-Bis(bromomethyl)biphenyl can I order?

We supply 4,4′-Bis(bromomethyl)biphenyl in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,4′-Bis(bromomethyl)biphenyl?

Yes. Every lot of 4,4′-Bis(bromomethyl)biphenyl is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,4′-Bis(bromomethyl)biphenyl be shipped internationally?

Yes. 4,4′-Bis(bromomethyl)biphenyl is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.