4,5-Dichloronicotinic Acid

Name: 4,5-Dichloronicotinic Acid
Brand: Vaqora Chemicals
SKU: VQ-047496

About 4,5-Dichloronicotinic Acid

Vaqora Chemicals supplies 4,5-Dichloronicotinic Acid, an impurity of Avatrombopag registered under CAS number 473837-10-4. Its molecular formula is C6H3Cl2NO2 and its molecular weight is 192.0 g/mol. Systematically, it is named 4,5-dichloropyridine-3-carboxylic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Avatrombopag, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Avatrombopag

View every impurity, metabolite and intermediate we list for Avatrombopag.

Avatrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	4,5-Dichloronicotinic Acid
Catalogue No.	VQ-047496
CAS Number	473837-10-4
IUPAC name	4,5-dichloropyridine-3-carboxylic acid
Molecular formula	C₆H₃Cl₂NO₂
Molecular weight	192 g/mol
Exact mass	190.9541
Grade	Reference Standard
HSN code	38229090
InChIKey	FLHXJEWJASHMBK-UHFFFAOYSA-N
SMILES	C1=C(C(=C(C=N1)Cl)Cl)C(=O)O
PubChem CID	2736089

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 3
TPSA	50.2 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,5-Dichloronicotinic Acid?

The CAS Registry Number of 4,5-Dichloronicotinic Acid is 473837-10-4.

What is the molecular formula and molecular weight of 4,5-Dichloronicotinic Acid?

4,5-Dichloronicotinic Acid has the molecular formula C6H3Cl2NO2 and a molecular weight of 192 g/mol. Its IUPAC name is 4,5-dichloropyridine-3-carboxylic acid.

What is 4,5-Dichloronicotinic Acid used for?

4,5-Dichloronicotinic Acid is supplied as a characterised reference material related to Avatrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,5-Dichloronicotinic Acid can I order?

We supply 4,5-Dichloronicotinic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,5-Dichloronicotinic Acid?

Yes. Every lot of 4,5-Dichloronicotinic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,5-Dichloronicotinic Acid be shipped internationally?

Yes. 4,5-Dichloronicotinic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.