4,5-Dimethoxy-1-benzocyclobutenecarbonitrile 35202-54-1

Name: 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
Brand: Vaqora Chemicals
SKU: VQ-031320

About 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile

Vaqora Chemicals supplies 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile, an impurity of Ivabradine registered under CAS number 35202-54-1. The compound has the formula C11H11NO2, corresponding to a molecular weight of 189.21 g/mol. Systematically, it is named 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile. It is also known as 4,5-Dimethoxy-1-cyanobenzocyclobutane or 45-Dimethoxy-1-cyanobenzocyclobutane.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 7 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Ivabradine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ivabradine

View every impurity, metabolite and intermediate we list for Ivabradine.

Ivabradine impurities

Specifications & identifiers

Chemical identifiers
Product name	4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
Catalogue No.	VQ-031320
CAS Number	35202-54-1
IUPAC name	3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile
Molecular formula	C₁₁H₁₁NO₂
Molecular weight	189.21 g/mol
Exact mass	189.079
Grade	Reference Standard
HSN code	38229090
InChIKey	HJTHVTHXHHFXMJ-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(CC2=C1)C#N)OC
PubChem CID	290544

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	0 / 3
TPSA	42.3 Å²
Synonyms	3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-triene-7-carbonitrile, 4,5-Dimethoxy-1-cyanobenzocyclobutane, 45-Dimethoxy-1-cyanobenzocyclobutane, 4,5-dimethoxy-1-cyano-benzocyclobutane, Bicyclo[4.2.0]aocta-a1,a3,a5-atriene-a7-acarbonitrile, 3,a4-adimethoxy-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile?

The CAS Registry Number of 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is 35202-54-1. It is also known as 3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-triene-7-carbonitrile, 4,5-Dimethoxy-1-cyanobenzocyclobutane, 45-Dimethoxy-1-cyanobenzocyclobutane.

What is the molecular formula and molecular weight of 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile?

4,5-Dimethoxy-1-benzocyclobutenecarbonitrile has the molecular formula C11H11NO2 and a molecular weight of 189.21 g/mol. Its IUPAC name is 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile.

What is 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile used for?

4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is supplied as a characterised reference material related to Ivabradine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile can I order?

We supply 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile?

Yes. Every lot of 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile be shipped internationally?

Yes. 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.