4,6-Dichloro-2-methylpyrimidine

Name: 4,6-Dichloro-2-methylpyrimidine
Brand: Vaqora Chemicals
SKU: VQ-013046

About 4,6-Dichloro-2-methylpyrimidine

Listed under CAS 1780-26-3, 4,6-Dichloro-2-methylpyrimidine is a process intermediate or related compound of Dasatinib available from Vaqora Chemicals. Its molecular formula is C5H4Cl2N2 and its molecular weight is 163.0 g/mol. It is also known as 2-Methyl-4,6-dichloropyrimidine or Pyrimidine, 4,6-dichloro-2-methyl-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Dasatinib, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 4,6-Dichloro-2-methylpyrimidine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dasatinib

View every impurity, metabolite and intermediate we list for Dasatinib.

Dasatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4,6-Dichloro-2-methylpyrimidine
Catalogue No.	VQ-013046
CAS Number	1780-26-3
IUPAC name	4,6-dichloro-2-methylpyrimidine
Molecular formula	C₅H₄Cl₂N₂
Molecular weight	163 g/mol
Exact mass	161.9752
Grade	Reference Standard
HSN code	2933
InChIKey	FIMUTBLUWQGTIJ-UHFFFAOYSA-N
SMILES	CC1=NC(=CC(=N1)Cl)Cl
PubChem CID	234997

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 2
TPSA	25.8 Å²
Synonyms	2-Methyl-4,6-dichloropyrimidine, Pyrimidine, 4,6-dichloro-2-methyl-, 4.6-dichloro-2-methyl pyrimidine, 4,6-Dichloro-2-methyl-pyrimidine, 2-methyl-4,6-dichloro-pyrimidine, 4,6-Dichloro-2-methylpyrimidine, 98%, 4,6-dichloro-2-methyl pyrimidine, 4,6-dichloro-2-methyip, 4,6-dichloro-2-methyipyrimidine, 4,6 dichloro-2-methyl pyrimidine

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P260, P261, P264, P270, P272, P273, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P330, P333 + P317, P362 + P364, P363, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,6-Dichloro-2-methylpyrimidine?

The CAS Registry Number of 4,6-Dichloro-2-methylpyrimidine is 1780-26-3. It is also known as 2-Methyl-4,6-dichloropyrimidine, Pyrimidine, 4,6-dichloro-2-methyl-, 4.6-dichloro-2-methyl pyrimidine.

What is the molecular formula and molecular weight of 4,6-Dichloro-2-methylpyrimidine?

4,6-Dichloro-2-methylpyrimidine has the molecular formula C5H4Cl2N2 and a molecular weight of 163 g/mol. Its IUPAC name is 4,6-dichloro-2-methylpyrimidine.

What is 4,6-Dichloro-2-methylpyrimidine used for?

4,6-Dichloro-2-methylpyrimidine is supplied as a characterised reference material related to Dasatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,6-Dichloro-2-methylpyrimidine can I order?

We supply 4,6-Dichloro-2-methylpyrimidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,6-Dichloro-2-methylpyrimidine?

Yes. Every lot of 4,6-Dichloro-2-methylpyrimidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,6-Dichloro-2-methylpyrimidine be shipped internationally?

Yes. 4,6-Dichloro-2-methylpyrimidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.