5-(2-Pyridyl)-1,2-dihydropyridin-2-one

Name: 5-(2-Pyridyl)-1,2-dihydropyridin-2-one
Brand: Vaqora Chemicals
SKU: VQ-027439

About 5-(2-Pyridyl)-1,2-dihydropyridin-2-one

Vaqora Chemicals supplies 5-(2-Pyridyl)-1,2-dihydropyridin-2-one, an impurity of Perampanel registered under CAS number 381233-78-9. Formula C10H8N2O, molecular weight 172.18 g/mol. Systematically, it is named 5-pyridin-2-yl-1H-pyridin-2-one. Alternative names: [2,3'-Bipyridin]-6'(1'H)-one and 5-(Pyridin-2-yl)-2(1H)-pyridone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Perampanel to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5-(2-Pyridyl)-1,2-dihydropyridin-2-one in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Perampanel

View every impurity, metabolite and intermediate we list for Perampanel.

Perampanel impurities

Specifications & identifiers

Chemical identifiers
Product name	5-(2-Pyridyl)-1,2-dihydropyridin-2-one
Catalogue No.	VQ-027439
CAS Number	381233-78-9
IUPAC name	5-pyridin-2-yl-1H-pyridin-2-one
Molecular formula	C₁₀H₈N₂O
Molecular weight	172.18 g/mol
Exact mass	172.0637
Grade	Reference Standard
HSN code	38229090
InChIKey	NHWKTZWOSIVHOL-UHFFFAOYSA-N
SMILES	C1=CC=NC(=C1)C2=CNC(=O)C=C2
PubChem CID	10241257

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	1 / 2
TPSA	42 Å²
Synonyms	[2,3'-Bipyridin]-6'(1'H)-one, 5-(Pyridin-2-yl)-2(1H)-pyridone, (2,3'-Bipyridin)-6'(1'H)-one, 5-(pyridin-2-yl)-1,2-dihydropyridin-2-one, 5-(2-Pyridyl)pyridin-2(1H)-one, 2,3'-bipyridin-6'-one, 2-Hydroxy-5-(2-pyridyl)pyridine, 5-Pyridin-2-yl-2(1H)-pyridone, 5-(2-pyridyl)-1H-pyridin-2-one, 5-Pyridin-2-yl-2 (1H)-pyridone, 1',6'-dihydro-[2,3'-bipyridine]-6'-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-(2-Pyridyl)-1,2-dihydropyridin-2-one?

The CAS Registry Number of 5-(2-Pyridyl)-1,2-dihydropyridin-2-one is 381233-78-9. It is also known as [2,3'-Bipyridin]-6'(1'H)-one, 5-(Pyridin-2-yl)-2(1H)-pyridone, (2,3'-Bipyridin)-6'(1'H)-one.

What is the molecular formula and molecular weight of 5-(2-Pyridyl)-1,2-dihydropyridin-2-one?

5-(2-Pyridyl)-1,2-dihydropyridin-2-one has the molecular formula C10H8N2O and a molecular weight of 172.18 g/mol. Its IUPAC name is 5-pyridin-2-yl-1H-pyridin-2-one.

What is 5-(2-Pyridyl)-1,2-dihydropyridin-2-one used for?

5-(2-Pyridyl)-1,2-dihydropyridin-2-one is supplied as a characterised reference material related to Perampanel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-(2-Pyridyl)-1,2-dihydropyridin-2-one can I order?

We supply 5-(2-Pyridyl)-1,2-dihydropyridin-2-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-(2-Pyridyl)-1,2-dihydropyridin-2-one?

Yes. Every lot of 5-(2-Pyridyl)-1,2-dihydropyridin-2-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-(2-Pyridyl)-1,2-dihydropyridin-2-one be shipped internationally?

Yes. 5-(2-Pyridyl)-1,2-dihydropyridin-2-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.