5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(… 67018-80-8

Name: 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile
Brand: Vaqora Chemicals
SKU: VQ-042857

About 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile

5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile (CAS 67018-80-8) is a metabolite or degradation product of Verapamil offered by Vaqora Chemicals. With the molecular formula C26H36N2O4, it has a molar mass of 440.6 g/mol. Its systematic (IUPAC) name is 5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(4-hydroxy-3-methoxyphenyl)-2-propan-2-ylpentanenitrile. Alternative names: O-Desmethylverapamil (D-703) and PR 23.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Verapamil, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Verapamil

View every impurity, metabolite and intermediate we list for Verapamil.

Verapamil impurities

Specifications & identifiers

Chemical identifiers
Product name	5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile
Catalogue No.	VQ-042857
CAS Number	67018-80-8
IUPAC name	5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(4-hydroxy-3-methoxyphenyl)-2-propan-2-ylpentanenitrile
Molecular formula	C₂₆H₃₆N₂O₄
Molecular weight	440.6 g/mol
Exact mass	440.2675
Grade	Reference Standard
HSN code	38229090
InChIKey	WLKVZSXOMGNZLB-UHFFFAOYSA-N
SMILES	CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)O)OC
PubChem CID	625729

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	1 / 6
TPSA	75 Å²
Synonyms	O-Desmethylverapamil (D-703), PR 23, (+/-)-PR-23, D-703, (+/-)-, Verapamil Metabolite (D-703), p-Hydroxy-isoptin

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile?

The CAS Registry Number of 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile is 67018-80-8. It is also known as O-Desmethylverapamil (D-703), PR 23, (+/-)-PR-23.

What is the molecular formula and molecular weight of 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile?

5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile has the molecular formula C26H36N2O4 and a molecular weight of 440.6 g/mol. Its IUPAC name is 5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(4-hydroxy-3-methoxyphenyl)-2-propan-2-ylpentanenitrile.

What is 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile used for?

5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile is supplied as a characterised reference material related to Verapamil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile can I order?

We supply 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile?

Yes. Every lot of 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile be shipped internationally?

Yes. We export 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(4-hydroxy-3-methoxyphenyl)-2-isopropylpentanenitrile worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.