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5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid

Synonyms: pazopanib sulfonic acid

CAS No.2795176-90-6
FormulaC21H22N6O3S
Mol. weight438.50
Catalogue No.VQ-041363
PurityReference Standard
HSN38229090

5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid (CAS 2795176-90-6) – Pazopanib impurity standard.

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About 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid

Vaqora Chemicals supplies 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid, an impurity of Pazopanib registered under CAS number 2795176-90-6. Formula C21H22N6O3S, molecular weight 438.5 g/mol. Systematically, it is named 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonic acid. Alternative names: pazopanib sulfonic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Pazopanib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

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Related to Pazopanib

View every impurity, metabolite and intermediate we list for Pazopanib.

Pazopanib impurities

Specifications & identifiers

Chemical identifiers
Product name5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid
Catalogue No.VQ-041363
CAS Number2795176-90-6
IUPAC name5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonic acid
Molecular formulaC21H22N6O3S
Molecular weight438.5 g/mol
Exact mass438.1474
GradeReference Standard
HSN code38229090
InChIKeyZFUQJYUAEBQQAN-UHFFFAOYSA-N
SMILESCC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)O
PubChem CID87148451
Physical properties
Physical formSolid
LogP (XLogP3)3.3
H-bond donors / acceptors2 / 8
TPSA122 Ų

Documents

Frequently asked questions

What is the CAS number of 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid?

The CAS Registry Number of 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid is 2795176-90-6. It is also known as pazopanib sulfonic acid.

What is the molecular formula and molecular weight of 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid?

5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid has the molecular formula C21H22N6O3S and a molecular weight of 438.5 g/mol. Its IUPAC name is 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonic acid.

What is 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid used for?

5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid is supplied as a characterised reference material related to Pazopanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid can I order?

We supply 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid?

Yes. Every lot of 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid be shipped internationally?

Yes. We export 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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