5-Azacytidine

Name: 5-Azacytidine
Brand: Vaqora Chemicals
SKU: VQ-013133

About 5-Azacytidine

Vaqora Chemicals supplies 5-Azacytidine, a process intermediate or related compound of Azacitidine registered under CAS number 320-67-2. Formula C8H12N4O5, molecular weight 244.2 g/mol. The IUPAC name is 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one. Common synonyms include Azacitidine and 5-AC.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Azacitidine, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Azacitidine

View every impurity, metabolite and intermediate we list for Azacitidine.

Azacitidine impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Azacytidine
Catalogue No.	VQ-013133
CAS Number	320-67-2
Other CAS	1401238-97-8
IUPAC name	4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
Molecular formula	C₈H₁₂N₄O₅
Molecular weight	244.2 g/mol
Exact mass	244.0808
Grade	Reference Standard
HSN code	2933
InChIKey	NMUSYJAQQFHJEW-KVTDHHQDSA-N
SMILES	C1=NC(=NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N
PubChem CID	9444

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.2
H-bond donors / acceptors	4 / 5
TPSA	141 Å²
Synonyms	4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one, Azacitidine, 5-AC, 5-AZC, 5-AZCR, 5-AzaC, Antibiotic U 18496, Ladakamycin, Ledakamycin, Mylosar, Vidaza, Azacytidine

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H350May cause cancer

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 320-67-2

5-Azacytidine, ≥98% (HPLC)

CAS: 320-67-2
Formula: C₈H₁₂N₄O₅
MW: 244.2 g/mol

VQ-012248

Cell Culture

5-Azacytidine, cell culture tested

CAS: 320-67-2
Formula: C₈H₁₂N₄O₅
MW: 244.2 g/mol

VQ-046103

Frequently asked questions

What is the CAS number of 5-Azacytidine?

The CAS Registry Number of 5-Azacytidine is 320-67-2. It is also known as 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one, Azacitidine, 5-AC.

What is the molecular formula and molecular weight of 5-Azacytidine?

5-Azacytidine has the molecular formula C8H12N4O5 and a molecular weight of 244.2 g/mol. Its IUPAC name is 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one.

What is 5-Azacytidine used for?

5-Azacytidine is supplied as a characterised reference material related to Azacitidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Azacytidine can I order?

We supply 5-Azacytidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Azacytidine?

Yes. Every lot of 5-Azacytidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Azacytidine be shipped internationally?

Yes. 5-Azacytidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.