5-Chloro-2-benzimidazolone

Name: 5-Chloro-2-benzimidazolone
Brand: Vaqora Chemicals
SKU: VQ-048071

About 5-Chloro-2-benzimidazolone

5-Chloro-2-benzimidazolone is a process intermediate or related compound of Domperidone carrying the CAS registry number 2034-23-3. With the molecular formula C7H5ClN2O, it has a molar mass of 168.58 g/mol. The IUPAC name is 5-chloro-1,3-dihydrobenzimidazol-2-one. It is also known as 5-chloro-1,3-dihydro-2H-benzimidazol-2-one or 5-Chloro-1,3-dihydrobenzoimidazol-2-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Domperidone, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5-Chloro-2-benzimidazolone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Domperidone

View every impurity, metabolite and intermediate we list for Domperidone.

Domperidone impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Chloro-2-benzimidazolone
Catalogue No.	VQ-048071
CAS Number	2034-23-3
IUPAC name	5-chloro-1,3-dihydrobenzimidazol-2-one
Molecular formula	C₇H₅ClN₂O
Molecular weight	168.58 g/mol
Exact mass	168.009
HSN code	2933
InChIKey	QIGIQLYKEULMQQ-UHFFFAOYSA-N
SMILES	C1=CC2=C(C=C1Cl)NC(=O)N2
PubChem CID	223131

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	2 / 1
TPSA	41.1 Å²
Synonyms	5-chloro-1,3-dihydro-2H-benzimidazol-2-one, 5-Chloro-1,3-dihydrobenzoimidazol-2-one, 5-Chloro-1H-benzo[d]imidazol-2(3H)-one, 5-chloro-1h-benzoimidazol-2-ol, 2H-Benzimidazol-2-one, 5-chloro-1,3-dihydro-, 5-Chloro-2-benzimidazolinone, 5-Chlorobenzimidazol-2(3H)-one, 5-chloro-2,3-dihydro-1H-1,3-benzodiazol-2-one, 5-chloro-1,3-dihydro-benzoimidazol-2-one, 5-chloro-3-hydrobenzimidazol-2-one, 5-chloro-1,3-dihydro-2H-benzo[d]imidazol-2-one, 5-chloro-1,3-d

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Chloro-2-benzimidazolone?

The CAS Registry Number of 5-Chloro-2-benzimidazolone is 2034-23-3. It is also known as 5-chloro-1,3-dihydro-2H-benzimidazol-2-one, 5-Chloro-1,3-dihydrobenzoimidazol-2-one, 5-Chloro-1H-benzo[d]imidazol-2(3H)-one.

What is the molecular formula and molecular weight of 5-Chloro-2-benzimidazolone?

5-Chloro-2-benzimidazolone has the molecular formula C7H5ClN2O and a molecular weight of 168.58 g/mol. Its IUPAC name is 5-chloro-1,3-dihydrobenzimidazol-2-one.

What is 5-Chloro-2-benzimidazolone used for?

5-Chloro-2-benzimidazolone is supplied as a characterised reference material related to Domperidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Chloro-2-benzimidazolone can I order?

We supply 5-Chloro-2-benzimidazolone, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Chloro-2-benzimidazolone?

Yes. Every lot of 5-Chloro-2-benzimidazolone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Chloro-2-benzimidazolone be shipped internationally?

Yes. 5-Chloro-2-benzimidazolone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.