5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one

Name: 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one
Brand: Vaqora Chemicals
SKU: VQ-047612

About 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one

Listed under CAS 5790-90-9, 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one is an impurity of Brensocatib available from Vaqora Chemicals. The compound has the formula C8H6ClNO2, corresponding to a molecular weight of 183.59 g/mol. The IUPAC name is 5-chloro-3-methyl-1,3-benzoxazol-2-one. Common synonyms include 5-Chloro-3-methyl-2-benzoxazolinone and 5-Chloro-3-methylbenzoxazol-2(3H)-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Brensocatib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Brensocatib

View every impurity, metabolite and intermediate we list for Brensocatib.

Brensocatib impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one
Catalogue No.	VQ-047612
CAS Number	5790-90-9
IUPAC name	5-chloro-3-methyl-1,3-benzoxazol-2-one
Molecular formula	C₈H₆ClNO₂
Molecular weight	183.59 g/mol
Exact mass	183.0087
Grade	Reference Standard
HSN code	38229090
InChIKey	VORWOQGVKPXSCM-UHFFFAOYSA-N
SMILES	CN1C2=C(C=CC(=C2)Cl)OC1=O
PubChem CID	22033

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	0 / 2
TPSA	29.5 Å²
Synonyms	5-Chloro-3-methyl-2-benzoxazolinone, 5-Chloro-3-methylbenzoxazol-2(3H)-one, 5-chloro-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one, 5-chloro-3-methyl-1,3-benzoxazol-2(3H)-one, 2(3H)-Benzoxazolone, 5-chloro-3-methyl-, Brensocatib Intermediate A, 3-methyl-5-chloro-2-benzoxazolone, 5-chloro-3-methyl-3-hydrobenzoxazol-2-one, 1,3-Benzoxazol-2(3H)-one, 5-chloro-3-methyl-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one?

The CAS Registry Number of 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one is 5790-90-9. It is also known as 5-Chloro-3-methyl-2-benzoxazolinone, 5-Chloro-3-methylbenzoxazol-2(3H)-one, 5-chloro-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one.

What is the molecular formula and molecular weight of 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one?

5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one has the molecular formula C8H6ClNO2 and a molecular weight of 183.59 g/mol. Its IUPAC name is 5-chloro-3-methyl-1,3-benzoxazol-2-one.

What is 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one used for?

5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one is supplied as a characterised reference material related to Brensocatib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one can I order?

We supply 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one?

Yes. Every lot of 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one be shipped internationally?

Yes. We export 5-Chloro-3-methylbenzo[d]oxazol-2(3H)-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.