5-(Chloroacetyl)oxindole

Name: 5-(Chloroacetyl)oxindole
Brand: Vaqora Chemicals
SKU: VQ-034747

About 5-(Chloroacetyl)oxindole

5-(Chloroacetyl)oxindole is an impurity of Ziprasidone carrying the CAS registry number 65435-04-3. With the molecular formula C10H8ClNO2, it has a molar mass of 209.63 g/mol. Its systematic (IUPAC) name is 5-(2-chloroacetyl)-1,3-dihydroindol-2-one. It is also known as 5-(Chloroacetyl)-1,3-dihydro-2H-indol-2-one or 5-(2-chloroacetyl)indolin-2-one.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Ziprasidone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5-(Chloroacetyl)oxindole in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ziprasidone

View every impurity, metabolite and intermediate we list for Ziprasidone.

Ziprasidone impurities

Specifications & identifiers

Chemical identifiers
Product name	5-(Chloroacetyl)oxindole
Catalogue No.	VQ-034747
CAS Number	65435-04-3
IUPAC name	5-(2-chloroacetyl)-1,3-dihydroindol-2-one
Molecular formula	C₁₀H₈ClNO₂
Molecular weight	209.63 g/mol
Exact mass	209.0244
Grade	Reference Standard
HSN code	38229090
InChIKey	WXJWBEAGVWVEDM-UHFFFAOYSA-N
SMILES	C1C2=C(C=CC(=C2)C(=O)CCl)NC1=O
PubChem CID	2060576

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	1 / 2
TPSA	46.2 Å²
Synonyms	5-(Chloroacetyl)-1,3-dihydro-2H-indol-2-one, 5-(2-chloroacetyl)indolin-2-one, 5-(2-chloroacetyl)-2,3-dihydro-1H-indol-2-one, 2H-Indol-2-one, 5-(chloroacetyl)-1,3-dihydro-, 5-Chloroacetyl-2-oxindole, 5-(2-Chloro-acetyl)-1,3-dihydro-indol-2-one, 5-(2-chloroacetyl)oxindole, 5-chloroacetylindolin-2-one, 5-(alpha-chloroacetyl)oxindol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-(Chloroacetyl)oxindole?

The CAS Registry Number of 5-(Chloroacetyl)oxindole is 65435-04-3. It is also known as 5-(Chloroacetyl)-1,3-dihydro-2H-indol-2-one, 5-(2-chloroacetyl)indolin-2-one, 5-(2-chloroacetyl)-2,3-dihydro-1H-indol-2-one.

What is the molecular formula and molecular weight of 5-(Chloroacetyl)oxindole?

5-(Chloroacetyl)oxindole has the molecular formula C10H8ClNO2 and a molecular weight of 209.63 g/mol. Its IUPAC name is 5-(2-chloroacetyl)-1,3-dihydroindol-2-one.

What is 5-(Chloroacetyl)oxindole used for?

5-(Chloroacetyl)oxindole is supplied as a characterised reference material related to Ziprasidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-(Chloroacetyl)oxindole can I order?

We supply 5-(Chloroacetyl)oxindole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-(Chloroacetyl)oxindole?

Yes. Every lot of 5-(Chloroacetyl)oxindole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-(Chloroacetyl)oxindole be shipped internationally?

Yes. 5-(Chloroacetyl)oxindole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.