5'-Deoxy-5'-(methylthio)adenosine

Name: 5'-Deoxy-5'-(methylthio)adenosine
Brand: Vaqora Chemicals
SKU: VQ-026321

About 5'-Deoxy-5'-(methylthio)adenosine

5'-Deoxy-5'-(methylthio)adenosine (CAS 2457-80-9) is an impurity of Adenosine offered by Vaqora Chemicals. With the molecular formula C11H15N5O3S, it has a molar mass of 297.34 g/mol. The IUPAC name is (2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol. It is also known as Methylthioadenosine or 5'-methylthioadenosine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Adenosine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Adenosine

View every impurity, metabolite and intermediate we list for Adenosine.

Adenosine impurities

Specifications & identifiers

Chemical identifiers
Product name	5'-Deoxy-5'-(methylthio)adenosine
Catalogue No.	VQ-026321
CAS Number	2457-80-9
IUPAC name	(2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol
Molecular formula	C₁₁H₁₅N₅O₃S
Molecular weight	297.34 g/mol
Exact mass	297.0896
Grade	Reference Standard
HSN code	38229090
InChIKey	WUUGFSXJNOTRMR-IOSLPCCCSA-N
SMILES	CSC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O
PubChem CID	439176

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	3 / 8
TPSA	145 Å²
Synonyms	Methylthioadenosine, 5'-methylthioadenosine, 5'-S-methyl-5'-thioadenosine, 5'-(Methylthio)adenosine, S-methyl-5'-thioadenosine, 5'-S-Methylthioadenosine, Vitamin L(sub 2), 5'-Deoxy(methylthio)adenosine, 5'-S-methyl-5'-thio-Adenosine, S-methyl-5-thioadenosine, (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methylsulfanyl)methyl]oxolane-3,4-diol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5'-Deoxy-5'-(methylthio)adenosine?

The CAS Registry Number of 5'-Deoxy-5'-(methylthio)adenosine is 2457-80-9. It is also known as Methylthioadenosine, 5'-methylthioadenosine, 5'-S-methyl-5'-thioadenosine.

What is the molecular formula and molecular weight of 5'-Deoxy-5'-(methylthio)adenosine?

5'-Deoxy-5'-(methylthio)adenosine has the molecular formula C11H15N5O3S and a molecular weight of 297.34 g/mol. Its IUPAC name is (2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol.

What is 5'-Deoxy-5'-(methylthio)adenosine used for?

5'-Deoxy-5'-(methylthio)adenosine is supplied as a characterised reference material related to Adenosine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5'-Deoxy-5'-(methylthio)adenosine can I order?

We supply 5'-Deoxy-5'-(methylthio)adenosine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5'-Deoxy-5'-(methylthio)adenosine?

Yes. Every lot of 5'-Deoxy-5'-(methylthio)adenosine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5'-Deoxy-5'-(methylthio)adenosine be shipped internationally?

Yes. 5'-Deoxy-5'-(methylthio)adenosine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.