5-epi Emtricitabine

Name: 5-epi Emtricitabine
Brand: Vaqora Chemicals
SKU: VQ-022517

About 5-epi Emtricitabine

5-epi Emtricitabine is an impurity of Emtricitabine carrying the CAS registry number 145986-26-1. The compound has the formula C8H10FN3O3S, corresponding to a molecular weight of 247.25 g/mol. Its systematic (IUPAC) name is 4-amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one. It is also known as Emtricitabine 5-Epimer or Oxathiolan 5FC-alpha.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Emtricitabine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 5-epi Emtricitabine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Emtricitabine

View every impurity, metabolite and intermediate we list for Emtricitabine.

Emtricitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	5-epi Emtricitabine
Catalogue No.	VQ-022517
CAS Number	145986-26-1
IUPAC name	4-amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Molecular formula	C₈H₁₀FN₃O₃S
Molecular weight	247.25 g/mol
Exact mass	247.0427
Grade	Reference Standard
HSN code	38229090
InChIKey	XQSPYNMVSIKCOC-PHDIDXHHSA-N
SMILES	C1[C@@H](O[C@H](S1)CO)N2C=C(C(=NC2=O)N)F
PubChem CID	454519

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.6
H-bond donors / acceptors	2 / 5
TPSA	113 Å²
Synonyms	Emtricitabine 5-Epimer, 5-epi Emtricitabine, Emtricitabine Diasteromer (RRT-1.23), Oxathiolan 5FC-alpha, alpha-L-FTC, alpha-L-(+)-(2R,5R)-5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine, 4-Amino-5-fluoro-1-((2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one, (2R,5R)-Emtricitabine, alpha-L-Oxathiolanyl-5-fluorocytidine, Emtricitabine hydrochloride, 4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, Oxathiolan 5FC-.a.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-epi Emtricitabine?

The CAS Registry Number of 5-epi Emtricitabine is 145986-26-1. It is also known as Emtricitabine 5-Epimer, 5-epi Emtricitabine, Emtricitabine Diasteromer (RRT-1.23), Oxathiolan 5FC-alpha.

What is the molecular formula and molecular weight of 5-epi Emtricitabine?

5-epi Emtricitabine has the molecular formula C8H10FN3O3S and a molecular weight of 247.25 g/mol. Its IUPAC name is 4-amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one.

What is 5-epi Emtricitabine used for?

5-epi Emtricitabine is supplied as a characterised reference material related to Emtricitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-epi Emtricitabine can I order?

We supply 5-epi Emtricitabine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-epi Emtricitabine?

Yes. Every lot of 5-epi Emtricitabine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-epi Emtricitabine be shipped internationally?

Yes. We export 5-epi Emtricitabine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.