5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b… 1350653-26-7

Name: 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
Brand: Vaqora Chemicals
SKU: VQ-034590

About 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile

Vaqora Chemicals supplies 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile, an impurity of Vericiguat registered under CAS number 1350653-26-7. The compound has the formula C14H8F2N4, corresponding to a molecular weight of 270.24 g/mol. The IUPAC name is 5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Vericiguat to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Vericiguat

View every impurity, metabolite and intermediate we list for Vericiguat.

Vericiguat impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
Catalogue No.	VQ-034590
CAS Number	1350653-26-7
IUPAC name	5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile
Molecular formula	C₁₄H₈F₂N₄
Molecular weight	270.24 g/mol
Exact mass	270.0717
Grade	Reference Standard
HSN code	38229090
InChIKey	GPEUANAWZCBBHU-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)CN2C3=C(C=C(C=N3)F)C(=N2)C#N)F
PubChem CID	56846743

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	0 / 5
TPSA	54.5 Å²
Synonyms	5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile, 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 5-fluoro-1-[(2-fluorophenyl)methyl]-, 5-fluoro-1- (2-fluorobenzyl)- 1H1pyrazolo[3,4-b]pyridine-3- carbonitrile, 5-Fluoro-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-3-carbonitrile, 5-fluoranyl-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile

Safety & hazard information (GHS)

Environmental hazard

Signal word: Warning

Hazard statements

H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P273, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile?

The CAS Registry Number of 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile is 1350653-26-7. It is also known as 5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile, 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 5-fluoro-1-[(2-fluorophenyl)methyl]-, 5-fluoro-1- (2-fluorobenzyl)- 1H1pyrazolo[3,4-b]pyridine-3- carbonitrile.

What is the molecular formula and molecular weight of 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile?

5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile has the molecular formula C14H8F2N4 and a molecular weight of 270.24 g/mol. Its IUPAC name is 5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile.

What is 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile used for?

5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile is supplied as a characterised reference material related to Vericiguat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile can I order?

We supply 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile?

Yes. Every lot of 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile be shipped internationally?

Yes. 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.