5-Hydroxy Desloratadine

Name: 5-Hydroxy Desloratadine
Brand: Vaqora Chemicals
SKU: VQ-038128

About 5-Hydroxy Desloratadine

5-Hydroxy Desloratadine (CAS 117811-12-8) is a metabolite or degradation product of Loratadine offered by Vaqora Chemicals. With the molecular formula C19H19ClN2O, it has a molar mass of 326.8 g/mol. The IUPAC name is 13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-9-ol. Common synonyms include 5-Hydroxy Desloratadine (Mixture of Isomers).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Loratadine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5-Hydroxy Desloratadine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Loratadine

View every impurity, metabolite and intermediate we list for Loratadine.

Loratadine impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Hydroxy Desloratadine
Catalogue No.	VQ-038128
CAS Number	117811-12-8
IUPAC name	13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-9-ol
Molecular formula	C₁₉H₁₉ClN₂O
Molecular weight	326.8 g/mol
Exact mass	326.1186
Grade	Reference Standard
HSN code	38229090
InChIKey	LWCSUGDLKORNAJ-UHFFFAOYSA-N
SMILES	C1CNCCC1=C2C3=C(CC(C4=C2N=CC=C4)O)C=C(C=C3)Cl
PubChem CID	14637775

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	2 / 3
TPSA	45.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Hydroxy Desloratadine?

The CAS Registry Number of 5-Hydroxy Desloratadine is 117811-12-8. It is also known as 5-Hydroxy Desloratadine (Mixture of Isomers), 5H-Benzo(5,6)cyclohepta(1,2-b)pyridin-5-ol, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-, 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-5-ol.

What is the molecular formula and molecular weight of 5-Hydroxy Desloratadine?

5-Hydroxy Desloratadine has the molecular formula C19H19ClN2O and a molecular weight of 326.8 g/mol. Its IUPAC name is 13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-9-ol.

What is 5-Hydroxy Desloratadine used for?

5-Hydroxy Desloratadine is supplied as a characterised reference material related to Loratadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Hydroxy Desloratadine can I order?

We supply 5-Hydroxy Desloratadine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Hydroxy Desloratadine?

Yes. Every lot of 5-Hydroxy Desloratadine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Hydroxy Desloratadine be shipped internationally?

Yes. We export 5-Hydroxy Desloratadine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.