5-Hydroxyesomeprazole

Name: 5-Hydroxyesomeprazole
Brand: Vaqora Chemicals
SKU: VQ-037082

About 5-Hydroxyesomeprazole

Listed under CAS 358675-51-1, 5-Hydroxyesomeprazole is a metabolite or degradation product of Esomeprazole available from Vaqora Chemicals. Its molecular formula is C16H17N3O3S and its molecular weight is 331.4 g/mol. Its systematic (IUPAC) name is 2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-3H-benzimidazol-5-ol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Esomeprazole, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 5-Hydroxyesomeprazole in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Esomeprazole

View every impurity, metabolite and intermediate we list for Esomeprazole.

Esomeprazole impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Hydroxyesomeprazole
Catalogue No.	VQ-037082
CAS Number	358675-51-1
IUPAC name	2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-3H-benzimidazol-5-ol
Molecular formula	C₁₆H₁₇N₃O₃S
Molecular weight	331.4 g/mol
Exact mass	331.0991
Grade	Reference Standard
HSN code	38229090
InChIKey	TWXDTVZNDQKCOS-QHCPKHFHSA-N
SMILES	CC1=CN=C(C(=C1OC)C)C[S@](=O)C2=NC3=C(N2)C=C(C=C3)O
PubChem CID	29918914

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 6
TPSA	107 Å²
Synonyms	(S)-2-(((4-Methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazol-6-ol, 1H-Benzimidazol-5-ol, 2-((S)-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-, 1H-Benzimidazol-6-ol, 2-((S)-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-, 2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-3H-benzimidazol-5-ol, (S)-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazol-5-ol, 2-[(S)-(4-Methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzimidazol-6-ol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Hydroxyesomeprazole?

The CAS Registry Number of 5-Hydroxyesomeprazole is 358675-51-1. It is also known as (S)-2-(((4-Methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazol-6-ol, 1H-Benzimidazol-5-ol, 2-((S)-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-, 1H-Benzimidazol-6-ol, 2-((S)-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-.

What is the molecular formula and molecular weight of 5-Hydroxyesomeprazole?

5-Hydroxyesomeprazole has the molecular formula C16H17N3O3S and a molecular weight of 331.4 g/mol. Its IUPAC name is 2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-3H-benzimidazol-5-ol.

What is 5-Hydroxyesomeprazole used for?

5-Hydroxyesomeprazole is supplied as a characterised reference material related to Esomeprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Hydroxyesomeprazole can I order?

We supply 5-Hydroxyesomeprazole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Hydroxyesomeprazole?

Yes. Every lot of 5-Hydroxyesomeprazole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Hydroxyesomeprazole be shipped internationally?

Yes. We export 5-Hydroxyesomeprazole worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.