5-Hydroxyindole-3-acetic Acid

Name: 5-Hydroxyindole-3-acetic Acid
Brand: Vaqora Chemicals
SKU: VQ-036259

About 5-Hydroxyindole-3-acetic Acid

Vaqora Chemicals supplies 5-Hydroxyindole-3-acetic Acid, a metabolite or degradation product of Tryptophan registered under CAS number 54-16-0. Formula C10H9NO3, molecular weight 191.18 g/mol. The IUPAC name is 2-(5-hydroxy-1H-indol-3-yl)acetic acid. It is also known as 5-Hydroxyindoleacetic Acid or 5-HIAA.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Tryptophan, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 5-Hydroxyindole-3-acetic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tryptophan

View every impurity, metabolite and intermediate we list for Tryptophan.

Tryptophan impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Hydroxyindole-3-acetic Acid
Catalogue No.	VQ-036259
CAS Number	54-16-0
IUPAC name	2-(5-hydroxy-1H-indol-3-yl)acetic acid
Molecular formula	C₁₀H₉NO₃
Molecular weight	191.18 g/mol
Exact mass	191.0582
Grade	Reference Standard
HSN code	38229090
InChIKey	DUUGKQCEGZLZNO-UHFFFAOYSA-N
SMILES	C1=CC2=C(C=C1O)C(=CN2)CC(=O)O
PubChem CID	1826

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	3 / 3
TPSA	73.3 Å²
Synonyms	5-Hydroxyindoleacetic Acid, 5-HIAA, Hydroxyindoleacetic acid, 5-Hydroxyindol-3-ylacetic acid, Acid, Hydroxyindoleacetic, 5-Hydroxyindolamine Acetic Acid, Acid, 5-Hydroxy-3-Indoleacetic, Acetic Acid, 5-Hydroxyindolamine, Acid, 5-Hydroxyindolamine Acetic, 2-(5-oxidanyl-1H-indol-2-yl)ethanoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Hydroxyindole-3-acetic Acid?

The CAS Registry Number of 5-Hydroxyindole-3-acetic Acid is 54-16-0. It is also known as 5-Hydroxyindoleacetic Acid, 5-HIAA, Hydroxyindoleacetic acid.

What is the molecular formula and molecular weight of 5-Hydroxyindole-3-acetic Acid?

5-Hydroxyindole-3-acetic Acid has the molecular formula C10H9NO3 and a molecular weight of 191.18 g/mol. Its IUPAC name is 2-(5-hydroxy-1H-indol-3-yl)acetic acid.

What is 5-Hydroxyindole-3-acetic Acid used for?

5-Hydroxyindole-3-acetic Acid is supplied as a characterised reference material related to Tryptophan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Hydroxyindole-3-acetic Acid can I order?

We supply 5-Hydroxyindole-3-acetic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Hydroxyindole-3-acetic Acid?

Yes. Every lot of 5-Hydroxyindole-3-acetic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Hydroxyindole-3-acetic Acid be shipped internationally?

Yes. 5-Hydroxyindole-3-acetic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.