5-Methyl-1,3,4-thiadiazol-2-ol

Name: 5-Methyl-1,3,4-thiadiazol-2-ol
Brand: Vaqora Chemicals
SKU: VQ-032528

About 5-Methyl-1,3,4-thiadiazol-2-ol

Listed under CAS 84352-65-8, 5-Methyl-1,3,4-thiadiazol-2-ol is an impurity of Rosuvastatin available from Vaqora Chemicals. With the molecular formula C3H4N2OS, it has a molar mass of 116.14 g/mol. Systematically, it is named 5-methyl-3H-1,3,4-thiadiazol-2-one. Alternative names: 5-Methyl-1,3,4-thiadiazol-2(3H)-one and 5-methyl-3H-[1,3,4]thiadiazol-2-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Rosuvastatin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 5-Methyl-1,3,4-thiadiazol-2-ol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rosuvastatin

View every impurity, metabolite and intermediate we list for Rosuvastatin.

Rosuvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Methyl-1,3,4-thiadiazol-2-ol
Catalogue No.	VQ-032528
CAS Number	84352-65-8
IUPAC name	5-methyl-3H-1,3,4-thiadiazol-2-one
Molecular formula	C₃H₄N₂OS
Molecular weight	116.14 g/mol
Exact mass	116.0044
Grade	Reference Standard
HSN code	38229090
InChIKey	FGLWYEULLSTVMA-UHFFFAOYSA-N
SMILES	CC1=NNC(=O)S1
PubChem CID	12816274

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	1 / 3
TPSA	66.8 Å²
Synonyms	5-Methyl-1,3,4-thiadiazol-2(3H)-one, 5-methyl-3H-[1,3,4]thiadiazol-2-one, 1,3,4-Thiadiazol-2(3H)-one, 5-methyl-, 1,3,4-thiadiazol-2-ol, 5-methyl-, 5-methyl-3H-[1.3.4]thiadiazol-2-one, 5-Methyl-1,3,4-thiadiazol-2-ol, AldrichCPR

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Methyl-1,3,4-thiadiazol-2-ol?

The CAS Registry Number of 5-Methyl-1,3,4-thiadiazol-2-ol is 84352-65-8. It is also known as 5-Methyl-1,3,4-thiadiazol-2(3H)-one, 5-methyl-3H-[1,3,4]thiadiazol-2-one, 1,3,4-Thiadiazol-2(3H)-one, 5-methyl-.

What is the molecular formula and molecular weight of 5-Methyl-1,3,4-thiadiazol-2-ol?

5-Methyl-1,3,4-thiadiazol-2-ol has the molecular formula C3H4N2OS and a molecular weight of 116.14 g/mol. Its IUPAC name is 5-methyl-3H-1,3,4-thiadiazol-2-one.

What is 5-Methyl-1,3,4-thiadiazol-2-ol used for?

5-Methyl-1,3,4-thiadiazol-2-ol is supplied as a characterised reference material related to Rosuvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Methyl-1,3,4-thiadiazol-2-ol can I order?

We supply 5-Methyl-1,3,4-thiadiazol-2-ol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Methyl-1,3,4-thiadiazol-2-ol?

Yes. Every lot of 5-Methyl-1,3,4-thiadiazol-2-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Methyl-1,3,4-thiadiazol-2-ol be shipped internationally?

Yes. 5-Methyl-1,3,4-thiadiazol-2-ol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.