5-Nitro-8-hydroxyquinoline

Name: 5-Nitro-8-hydroxyquinoline
Brand: Vaqora Chemicals
SKU: VQ-038676

About 5-Nitro-8-hydroxyquinoline

5-Nitro-8-hydroxyquinoline is a high-purity reference standard of Nitroxoline carrying the CAS registry number 4008-48-4. With the molecular formula C9H6N2O3, it has a molar mass of 190.16 g/mol. Its systematic (IUPAC) name is 5-nitroquinolin-8-ol. It is also known as Nitroxoline or 8-Hydroxy-5-nitroquinoline.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Nitroxoline standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 5-Nitro-8-hydroxyquinoline in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material
Fine chemical synthesis

Industries

Related to Nitroxoline

View every impurity, metabolite and intermediate we list for Nitroxoline.

Nitroxoline impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Nitro-8-hydroxyquinoline
Catalogue No.	VQ-038676
CAS Number	4008-48-4
IUPAC name	5-nitroquinolin-8-ol
Molecular formula	C₉H₆N₂O₃
Molecular weight	190.16 g/mol
Exact mass	190.0378
Grade	Reference Standard
HSN code	38229090
InChIKey	RJIWZDNTCBHXAL-UHFFFAOYSA-N
SMILES	C1=CC2=C(C=CC(=C2N=C1)O)[N+](=O)[O-]
PubChem CID	19910

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 4
TPSA	78.9 Å²
Synonyms	Nitroxoline, 8-Hydroxy-5-nitroquinoline, 5-Nitro-8-quinolinol, 5-Nitrox, 5-NOK, 5-Nitro-8-oxyquinoline, 5NOK, Nicene, Nitroxolin, Noxibiol, Nibiol, Noxin

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P319, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Nitro-8-hydroxyquinoline?

The CAS Registry Number of 5-Nitro-8-hydroxyquinoline is 4008-48-4. It is also known as Nitroxoline, 8-Hydroxy-5-nitroquinoline, 5-Nitro-8-quinolinol.

What is the molecular formula and molecular weight of 5-Nitro-8-hydroxyquinoline?

5-Nitro-8-hydroxyquinoline has the molecular formula C9H6N2O3 and a molecular weight of 190.16 g/mol. Its IUPAC name is 5-nitroquinolin-8-ol.

What is 5-Nitro-8-hydroxyquinoline used for?

5-Nitro-8-hydroxyquinoline is supplied as a characterised reference material related to Nitroxoline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Nitro-8-hydroxyquinoline can I order?

We supply 5-Nitro-8-hydroxyquinoline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Nitro-8-hydroxyquinoline?

Yes. Every lot of 5-Nitro-8-hydroxyquinoline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Nitro-8-hydroxyquinoline be shipped internationally?

Yes. 5-Nitro-8-hydroxyquinoline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.