5-Nitrosoquinolin-8-ol

Name: 5-Nitrosoquinolin-8-ol
Brand: Vaqora Chemicals
SKU: VQ-039674

About 5-Nitrosoquinolin-8-ol

Listed under CAS 3565-26-2, 5-Nitrosoquinolin-8-ol is a nitrosamine impurity of Fludarabine available from Vaqora Chemicals. The compound has the formula C9H6N2O2, corresponding to a molecular weight of 174.16 g/mol. Common synonyms include 5-Nitroso-8-quinolinol and 5-Nitroso-8-hydroxyquinoline.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5-Nitrosoquinolin-8-ol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Fludarabine

View every impurity, metabolite and intermediate we list for Fludarabine.

Fludarabine impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Nitrosoquinolin-8-ol
Catalogue No.	VQ-039674
CAS Number	3565-26-2
IUPAC name	5-nitrosoquinolin-8-ol
Molecular formula	C₉H₆N₂O₂
Molecular weight	174.16 g/mol
Exact mass	174.0429
Grade	Reference Standard
HSN code	38229090
InChIKey	RZWRYPGAUIOOMK-UHFFFAOYSA-N
SMILES	C1=CC2=C(C=CC(=C2N=C1)O)N=O
PubChem CID	19103

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 4
TPSA	62.6 Å²
Synonyms	5-Nitroso-8-quinolinol, 5-Nitroso-8-hydroxyquinoline, Hydron III, 5-Nitrosooxine, 8-Hydroxy-5-nitrosoquinoline, 5-Nitroso-8-cinnolinol, RMH-79, quinoline, 8-hydroxy-5-nitroso-, 5-Nitroso-oxine, 5-(hydroxyimino)quinolin-8-one

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Nitrosoquinolin-8-ol?

The CAS Registry Number of 5-Nitrosoquinolin-8-ol is 3565-26-2. It is also known as 5-Nitroso-8-quinolinol, 5-Nitroso-8-hydroxyquinoline, Hydron III.

What is the molecular formula and molecular weight of 5-Nitrosoquinolin-8-ol?

5-Nitrosoquinolin-8-ol has the molecular formula C9H6N2O2 and a molecular weight of 174.16 g/mol. Its IUPAC name is 5-nitrosoquinolin-8-ol.

What is 5-Nitrosoquinolin-8-ol used for?

5-Nitrosoquinolin-8-ol is supplied as a characterised reference material related to Fludarabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Nitrosoquinolin-8-ol can I order?

We supply 5-Nitrosoquinolin-8-ol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Nitrosoquinolin-8-ol?

Yes. Every lot of 5-Nitrosoquinolin-8-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Nitrosoquinolin-8-ol be shipped internationally?

Yes. 5-Nitrosoquinolin-8-ol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.