6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-di… 6972-27-6

Name: 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
Brand: Vaqora Chemicals
SKU: VQ-025849

About 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

Vaqora Chemicals supplies 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione, an impurity of Fluorouracil registered under CAS number 6972-27-6. The compound has the formula C6H7ClN2O2, corresponding to a molecular weight of 174.58 g/mol. Systematically, it is named 6-chloro-1,3-dimethylpyrimidine-2,4-dione. Alternative names: 6-Chloro-1,3-Dimethyluracil and 1,3-Dimethyl-6-chlorouracil.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Fluorouracil, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Fluorouracil

View every impurity, metabolite and intermediate we list for Fluorouracil.

Fluorouracil impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
Catalogue No.	VQ-025849
CAS Number	6972-27-6
IUPAC name	6-chloro-1,3-dimethylpyrimidine-2,4-dione
Molecular formula	C₆H₇ClN₂O₂
Molecular weight	174.58 g/mol
Exact mass	174.0196
Grade	Reference Standard
HSN code	38229090
InChIKey	VATQPUHLFQHDBD-UHFFFAOYSA-N
SMILES	CN1C(=CC(=O)N(C1=O)C)Cl
PubChem CID	81442

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	0 / 2
TPSA	40.6 Å²
Synonyms	6-Chloro-1,3-Dimethyluracil, 6-chloro-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione, 1,3-Dimethyl-6-chlorouracil, 2,4(1H,3H)-Pyrimidinedione, 6-chloro-1,3-dimethyl-, 6-chloro-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, 6-Chloro-2,4-dihydroxy-1,3-dimethylpyrimidine, 6-Chloro-1,3-dimethyl-2,4-(1H,3H)-pyrimidinedione, 6-chloro-1,3-dimethyl-1,3-dihydropyrimidine-2,4-dione, 1,3-Dimethyl-6-, 1,3-Dimethyl-4-chlorouracil, 6-chloro-1,3-dimethyl-2,4-dioxopyrimidine

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione?

The CAS Registry Number of 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione is 6972-27-6. It is also known as 6-Chloro-1,3-Dimethyluracil, 6-chloro-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione, 1,3-Dimethyl-6-chlorouracil.

What is the molecular formula and molecular weight of 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione?

6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione has the molecular formula C6H7ClN2O2 and a molecular weight of 174.58 g/mol. Its IUPAC name is 6-chloro-1,3-dimethylpyrimidine-2,4-dione.

What is 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione used for?

6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione is supplied as a characterised reference material related to Fluorouracil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione can I order?

We supply 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione?

Yes. Every lot of 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione be shipped internationally?

Yes. 6-Chloro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.