6-Desamino 6-Chloro Etravirine

Name: 6-Desamino 6-Chloro Etravirine
Brand: Vaqora Chemicals
SKU: VQ-037160

About 6-Desamino 6-Chloro Etravirine

6-Desamino 6-Chloro Etravirine (CAS 269055-76-7) is an impurity of Etravirine offered by Vaqora Chemicals. Its molecular formula is C20H13BrClN5O and its molecular weight is 454.7 g/mol. Systematically, it is named 4-[5-bromo-6-chloro-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Etravirine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 6-Desamino 6-Chloro Etravirine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Etravirine

View every impurity, metabolite and intermediate we list for Etravirine.

Etravirine impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Desamino 6-Chloro Etravirine
Catalogue No.	VQ-037160
CAS Number	269055-76-7
IUPAC name	4-[5-bromo-6-chloro-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile
Molecular formula	C₂₀H₁₃BrClN₅O
Molecular weight	454.7 g/mol
Exact mass	452.9992
Grade	Reference Standard
HSN code	38229090
InChIKey	ODWHQRYHASBLKO-UHFFFAOYSA-N
SMILES	CC1=CC(=CC(=C1OC2=C(C(=NC(=N2)NC3=CC=C(C=C3)C#N)Cl)Br)C)C#N
PubChem CID	11751416

Physical properties
Physical form	Solid
LogP (XLogP3)	5.8
H-bond donors / acceptors	1 / 6
TPSA	94.6 Å²
Synonyms	4-[[5-Bromo-6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile, 4-((5-Bromo-6-chloro-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethylbenzonitrile, 4-[[5-bromo-4-(4-cyano-2,6-dimethylpbenoxy)-6-chloro-2-pyrimidinyl]amino]-benzonitrile, 4-[[5-bromo-4-(4-cyano-2,6-dimethylphenoxy)-6-chloro-2-pyrimidiny]amino]-benzonitrile, 4-[[5-bromo-4-(4-cyano-2,6-dimethylphenoxy)-6-chloro-2-pyrimidinyl]amino]-benzonitrile, 4-[[5-bromo-4-(4-cyano-2,6-dimethylphenoxy)-6-chloro-2-pyrimidinyl]amino]benzonitrile, 4-[[5-bromo4-(4-cyano-2,6-dimethylphenoxy)-6-chloro-2-pyrimidinyl]amino]-benzonitrile, 4-[[5-bromo4-(4-cyano-2,6-dimethylphenoxy)-6-chloro-2-pyrimidinyl]amino]benzonitrile, 4-{[5-Bromo-6-chloro-2-(4-cyanoanilino)pyrimidin-4-yl]oxy}-3,5-dimethylbenzonitrile

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Desamino 6-Chloro Etravirine?

The CAS Registry Number of 6-Desamino 6-Chloro Etravirine is 269055-76-7. It is also known as 4-[[5-Bromo-6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile, 4-((5-Bromo-6-chloro-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethylbenzonitrile, 4-[[5-bromo-4-(4-cyano-2,6-dimethylpbenoxy)-6-chloro-2-pyrimidinyl]amino]-benzonitrile.

What is the molecular formula and molecular weight of 6-Desamino 6-Chloro Etravirine?

6-Desamino 6-Chloro Etravirine has the molecular formula C20H13BrClN5O and a molecular weight of 454.7 g/mol. Its IUPAC name is 4-[5-bromo-6-chloro-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile.

What is 6-Desamino 6-Chloro Etravirine used for?

6-Desamino 6-Chloro Etravirine is supplied as a characterised reference material related to Etravirine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Desamino 6-Chloro Etravirine can I order?

We supply 6-Desamino 6-Chloro Etravirine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Desamino 6-Chloro Etravirine?

Yes. Every lot of 6-Desamino 6-Chloro Etravirine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Desamino 6-Chloro Etravirine be shipped internationally?

Yes. We export 6-Desamino 6-Chloro Etravirine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.