6-Hydroxyhyoscyamine

Name: 6-Hydroxyhyoscyamine
Brand: Vaqora Chemicals
SKU: VQ-024427

About 6-Hydroxyhyoscyamine

6-Hydroxyhyoscyamine (CAS 55869-99-3) is a metabolite or degradation product of Atropine offered by Vaqora Chemicals. With the molecular formula C17H23NO4, it has a molar mass of 305.4 g/mol. Systematically, it is named [(1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate. Common synonyms include 6(S)-Hydroxyhyoscyamine and anisodamine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Atropine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 6-Hydroxyhyoscyamine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Atropine

View every impurity, metabolite and intermediate we list for Atropine.

Atropine impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Hydroxyhyoscyamine
Catalogue No.	VQ-024427
CAS Number	55869-99-3
IUPAC name	[(1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate
Molecular formula	C₁₇H₂₃NO₄
Molecular weight	305.4 g/mol
Exact mass	305.1627
Grade	Reference Standard
HSN code	38229090
InChIKey	WTQYWNWRJNXDEG-RBZJEDDUSA-N
SMILES	CN1[C@H]2C[C@@H](C[C@@H]1[C@H](C2)O)OC(=O)[C@H](CO)C3=CC=CC=C3
PubChem CID	6918612

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	2 / 5
TPSA	70 Å²
Synonyms	6(S)-Hydroxyhyoscyamine, anisodamine, Hyoscyamine, 6-hydroxy-, (-)-6beta-hydroxyhyoscyamine, Anisodamine, (+/-)-, Raceanisodamine, 6.beta.-Hydroxyhyoscyamine, (-)-6.beta.-hydroxyhyoscyamine, (-)-Anisodamine, 654-II, D-anisodamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Hydroxyhyoscyamine?

The CAS Registry Number of 6-Hydroxyhyoscyamine is 55869-99-3. It is also known as 6(S)-Hydroxyhyoscyamine, anisodamine, Hyoscyamine, 6-hydroxy-.

What is the molecular formula and molecular weight of 6-Hydroxyhyoscyamine?

6-Hydroxyhyoscyamine has the molecular formula C17H23NO4 and a molecular weight of 305.4 g/mol. Its IUPAC name is [(1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate.

What is 6-Hydroxyhyoscyamine used for?

6-Hydroxyhyoscyamine is supplied as a characterised reference material related to Atropine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Hydroxyhyoscyamine can I order?

We supply 6-Hydroxyhyoscyamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Hydroxyhyoscyamine?

Yes. Every lot of 6-Hydroxyhyoscyamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Hydroxyhyoscyamine be shipped internationally?

Yes. 6-Hydroxyhyoscyamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.