6-O-Demethyl Griseofulvin

Name: 6-O-Demethyl Griseofulvin
Brand: Vaqora Chemicals
SKU: VQ-048560

About 6-O-Demethyl Griseofulvin

6-O-Demethyl Griseofulvin is a metabolite or degradation product of Griseofulvin carrying the CAS registry number 20168-88-1. Formula C16H15ClO6, molecular weight 338.74 g/mol. Systematically, it is named (2S,5'R)-7-chloro-6-hydroxy-3',4-dimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione. It is also known as Griseofulvin 6-O-Demethyl or 6-Demethylgriseofulvin.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Griseofulvin, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 6-O-Demethyl Griseofulvin in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Griseofulvin

View every impurity, metabolite and intermediate we list for Griseofulvin.

Griseofulvin impurities

Specifications & identifiers

Chemical identifiers
Product name	6-O-Demethyl Griseofulvin
Catalogue No.	VQ-048560
CAS Number	20168-88-1
IUPAC name	(2S,5'R)-7-chloro-6-hydroxy-3',4-dimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
Molecular formula	C₁₆H₁₅ClO₆
Molecular weight	338.74 g/mol
Exact mass	338.0557
Grade	Reference Standard
HSN code	38229090
InChIKey	SYNGDIBHUPXIQA-QZTNRIJFSA-N
SMILES	C[C@@H]1CC(=O)C=C([C@]12C(=O)C3=C(C=C(C(=C3O2)Cl)O)OC)OC
PubChem CID	9974417

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	1 / 6
TPSA	82.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-O-Demethyl Griseofulvin?

The CAS Registry Number of 6-O-Demethyl Griseofulvin is 20168-88-1. It is also known as Griseofulvin 6-O-Demethyl, 6-Demethylgriseofulvin, 6-Desmethylgriseofulvin.

What is the molecular formula and molecular weight of 6-O-Demethyl Griseofulvin?

6-O-Demethyl Griseofulvin has the molecular formula C16H15ClO6 and a molecular weight of 338.74 g/mol. Its IUPAC name is (2S,5'R)-7-chloro-6-hydroxy-3',4-dimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione.

What is 6-O-Demethyl Griseofulvin used for?

6-O-Demethyl Griseofulvin is supplied as a characterised reference material related to Griseofulvin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-O-Demethyl Griseofulvin can I order?

We supply 6-O-Demethyl Griseofulvin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-O-Demethyl Griseofulvin?

Yes. Every lot of 6-O-Demethyl Griseofulvin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-O-Demethyl Griseofulvin be shipped internationally?

Yes. We export 6-O-Demethyl Griseofulvin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.