6Alpha-Methyl-21-desoxycortisol

Name: 6Alpha-Methyl-21-desoxycortisol
Brand: Vaqora Chemicals
SKU: VQ-038369

About 6Alpha-Methyl-21-desoxycortisol

Listed under CAS 7055-53-0, 6Alpha-Methyl-21-desoxycortisol is an impurity of Methylprednisolone available from Vaqora Chemicals. Formula C22H32O4, molecular weight 360.5 g/mol. Common synonyms include 11beta-Hydroxymedroxyprogesterone.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Methylprednisolone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 6Alpha-Methyl-21-desoxycortisol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methylprednisolone

View every impurity, metabolite and intermediate we list for Methylprednisolone.

Methylprednisolone impurities

Specifications & identifiers

Chemical identifiers
Product name	6Alpha-Methyl-21-desoxycortisol
Catalogue No.	VQ-038369
CAS Number	7055-53-0
IUPAC name	(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₃₂O₄
Molecular weight	360.5 g/mol
Exact mass	360.2301
Grade	Reference Standard
HSN code	38229090
InChIKey	VSGTWMOZGFNRPM-RSWUNGFYSA-N
SMILES	C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)CC4)C)O)C)(C(=O)C)O
PubChem CID	243748

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 4
TPSA	74.6 Å²
Synonyms	(6alpha,11beta)-11,17-Dihydroxy-6-methylpregn-4-ene-3,20-dione, 11beta-17-Dihydroxy-6alpha-methylpregn-4-ene-3,20-dione, 6alpha-Methyl-11beta,17alpha-dihydroxyprogesterone, 11beta-Hydroxymedroxyprogesterone, Pregn-4-ene-3,20-dione, 11.beta.,17-dihydroxy-6.alpha.-methyl-, 11,17-Dihydroxy-6alpha-methylpregn-4-ene-3,20-dione, Progesterone, 11.beta.,17-dihydroxy-6.alpha.-methyl-, 11beta,17-dihydroxy-6alpha-methyl-pregn-4-ene-3,20-dione, 11beta,17-dihydroxy-6alpha-Methylpregne-4-en-3,20-dione, Pregn-4-ene-3, 11.beta.,17-dihydroxy-6.alpha.-methyl-, (6I+/-,11I(2))-11,17-Dihydroxy-6-methylpregn-4-ene-3,20-dione

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H373May causes damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P260, P273, P319, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6Alpha-Methyl-21-desoxycortisol?

The CAS Registry Number of 6Alpha-Methyl-21-desoxycortisol is 7055-53-0. It is also known as (6alpha,11beta)-11,17-Dihydroxy-6-methylpregn-4-ene-3,20-dione, 11beta-17-Dihydroxy-6alpha-methylpregn-4-ene-3,20-dione, 6alpha-Methyl-11beta,17alpha-dihydroxyprogesterone.

What is the molecular formula and molecular weight of 6Alpha-Methyl-21-desoxycortisol?

6Alpha-Methyl-21-desoxycortisol has the molecular formula C22H32O4 and a molecular weight of 360.5 g/mol. Its IUPAC name is (6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.

What is 6Alpha-Methyl-21-desoxycortisol used for?

6Alpha-Methyl-21-desoxycortisol is supplied as a characterised reference material related to Methylprednisolone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6Alpha-Methyl-21-desoxycortisol can I order?

We supply 6Alpha-Methyl-21-desoxycortisol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6Alpha-Methyl-21-desoxycortisol?

Yes. Every lot of 6Alpha-Methyl-21-desoxycortisol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6Alpha-Methyl-21-desoxycortisol be shipped internationally?

Yes. 6Alpha-Methyl-21-desoxycortisol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.