(6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-… 2353-16-4

Name: (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione
Brand: Vaqora Chemicals
SKU: VQ-044390

About (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione

(6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione is an impurity of Fluocinolone acetonide carrying the CAS registry number 2353-16-4. Its molecular formula is C21H26F2O4 and its molecular weight is 380.4 g/mol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Fluocinolone acetonide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Fluocinolone acetonide

View every impurity, metabolite and intermediate we list for Fluocinolone acetonide.

Fluocinolone acetonide impurities

Specifications & identifiers

Chemical identifiers
Product name	(6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione
Catalogue No.	VQ-044390
CAS Number	2353-16-4
IUPAC name	(6S,8S,9R,10S,11S,13S,14S,17S)-6,9-difluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₁H₂₆F₂O₄
Molecular weight	380.4 g/mol
Exact mass	380.1799
Grade	Reference Standard
HSN code	38229090
InChIKey	HCUJCITVYDARMA-PAPZHHRGSA-N
SMILES	C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1CC[C@@H]2C(=O)CO)C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O
PubChem CID	141022553

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	2 / 6
TPSA	74.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione?

The CAS Registry Number of (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione is 2353-16-4.

What is the molecular formula and molecular weight of (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione?

(6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione has the molecular formula C21H26F2O4 and a molecular weight of 380.4 g/mol. Its IUPAC name is (6S,8S,9R,10S,11S,13S,14S,17S)-6,9-difluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one.

What is (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione used for?

(6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione is supplied as a characterised reference material related to Fluocinolone acetonide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione can I order?

We supply (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione?

Yes. Every lot of (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione be shipped internationally?

Yes. We export (6α,11β)-6,9-Difluoro-11,21-dihydroxy-pregna-1,4-diene-3,20-dione worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.