7-(-β-Hydroxypropyl)theophylline

Name: 7-(-β-Hydroxypropyl)theophylline
Brand: Vaqora Chemicals
SKU: VQ-027676

About 7-(-β-Hydroxypropyl)theophylline

Listed under CAS 603-00-9, 7-(-β-Hydroxypropyl)theophylline is a metabolite or degradation product of Diprophylline available from Vaqora Chemicals. Its molecular formula is C10H14N4O3 and its molecular weight is 238.24 g/mol. Systematically, it is named 7-(2-hydroxypropyl)-1,3-dimethylpurine-2,6-dione. It is also known as Proxyphylline or Purophyllin.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Diprophylline, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 7-(-β-Hydroxypropyl)theophylline is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Diprophylline

View every impurity, metabolite and intermediate we list for Diprophylline.

Diprophylline impurities

Specifications & identifiers

Chemical identifiers
Product name	7-(-β-Hydroxypropyl)theophylline
Catalogue No.	VQ-027676
CAS Number	603-00-9
IUPAC name	7-(2-hydroxypropyl)-1,3-dimethylpurine-2,6-dione
Molecular formula	C₁₀H₁₄N₄O₃
Molecular weight	238.24 g/mol
Exact mass	238.1066
Grade	Reference Standard
HSN code	38229090
InChIKey	KYHQZNGJUGFTGR-UHFFFAOYSA-N
SMILES	CC(CN1C=NC2=C1C(=O)N(C(=O)N2C)C)O
PubChem CID	4977

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.8
H-bond donors / acceptors	1 / 4
TPSA	78.7 Å²
Synonyms	Proxyphylline, Purophyllin, Brontyl, 7-(2-Hydroxypropyl)theophylline, Proxiphylline, Spasmolysin, Oxypropyltheophylline, Sigophyl, Spantin, beta-Oxypropyltheophyllin, 2-Hydroxypropyl-7-theophylline, Monophyllin

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 7-(-β-Hydroxypropyl)theophylline?

The CAS Registry Number of 7-(-β-Hydroxypropyl)theophylline is 603-00-9. It is also known as Proxyphylline, Purophyllin, Brontyl.

What is the molecular formula and molecular weight of 7-(-β-Hydroxypropyl)theophylline?

7-(-β-Hydroxypropyl)theophylline has the molecular formula C10H14N4O3 and a molecular weight of 238.24 g/mol. Its IUPAC name is 7-(2-hydroxypropyl)-1,3-dimethylpurine-2,6-dione.

What is 7-(-β-Hydroxypropyl)theophylline used for?

7-(-β-Hydroxypropyl)theophylline is supplied as a characterised reference material related to Diprophylline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 7-(-β-Hydroxypropyl)theophylline can I order?

We supply 7-(-β-Hydroxypropyl)theophylline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 7-(-β-Hydroxypropyl)theophylline?

Yes. Every lot of 7-(-β-Hydroxypropyl)theophylline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 7-(-β-Hydroxypropyl)theophylline be shipped internationally?

Yes. 7-(-β-Hydroxypropyl)theophylline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.