7-Chloro-3,4-dihydroquinolin-2(1H)-one

Name: 7-Chloro-3,4-dihydroquinolin-2(1H)-one
Brand: Vaqora Chemicals
SKU: VQ-032681

About 7-Chloro-3,4-dihydroquinolin-2(1H)-one

7-Chloro-3,4-dihydroquinolin-2(1H)-one (CAS 14548-50-6) is an impurity of Aripiprazole offered by Vaqora Chemicals. The compound has the formula C9H8ClNO, corresponding to a molecular weight of 181.62 g/mol. The IUPAC name is 7-chloro-3,4-dihydro-1H-quinolin-2-one. Alternative names: 7-chloro-1,2,3,4-tetrahydroquinolin-2-one and 2(1H)-Quinolinone, 7-chloro-3,4-dihydro-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Aripiprazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 7-Chloro-3,4-dihydroquinolin-2(1H)-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Aripiprazole

View every impurity, metabolite and intermediate we list for Aripiprazole.

Aripiprazole impurities

Specifications & identifiers

Chemical identifiers
Product name	7-Chloro-3,4-dihydroquinolin-2(1H)-one
Catalogue No.	VQ-032681
CAS Number	14548-50-6
IUPAC name	7-chloro-3,4-dihydro-1H-quinolin-2-one
Molecular formula	C₉H₈ClNO
Molecular weight	181.62 g/mol
Exact mass	181.0294
Grade	Reference Standard
HSN code	38229090
InChIKey	HBKUREOLTIMYPY-UHFFFAOYSA-N
SMILES	C1CC(=O)NC2=C1C=CC(=C2)Cl
PubChem CID	13690766

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	1 / 1
TPSA	29.1 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 7-Chloro-3,4-dihydroquinolin-2(1H)-one?

The CAS Registry Number of 7-Chloro-3,4-dihydroquinolin-2(1H)-one is 14548-50-6. It is also known as 7-chloro-1,2,3,4-tetrahydroquinolin-2-one, 2(1H)-Quinolinone, 7-chloro-3,4-dihydro-, 7-chloro-3,4-dihydro-2(1H)-quinolinone.

What is the molecular formula and molecular weight of 7-Chloro-3,4-dihydroquinolin-2(1H)-one?

7-Chloro-3,4-dihydroquinolin-2(1H)-one has the molecular formula C9H8ClNO and a molecular weight of 181.62 g/mol. Its IUPAC name is 7-chloro-3,4-dihydro-1H-quinolin-2-one.

What is 7-Chloro-3,4-dihydroquinolin-2(1H)-one used for?

7-Chloro-3,4-dihydroquinolin-2(1H)-one is supplied as a characterised reference material related to Aripiprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 7-Chloro-3,4-dihydroquinolin-2(1H)-one can I order?

We supply 7-Chloro-3,4-dihydroquinolin-2(1H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 7-Chloro-3,4-dihydroquinolin-2(1H)-one?

Yes. Every lot of 7-Chloro-3,4-dihydroquinolin-2(1H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 7-Chloro-3,4-dihydroquinolin-2(1H)-one be shipped internationally?

Yes. 7-Chloro-3,4-dihydroquinolin-2(1H)-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.