7-Chloro-4-hydroxyquinoline-3-carboxylic acid

Name: 7-Chloro-4-hydroxyquinoline-3-carboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-037604

About 7-Chloro-4-hydroxyquinoline-3-carboxylic acid

Vaqora Chemicals supplies 7-Chloro-4-hydroxyquinoline-3-carboxylic acid, a metabolite or degradation product of Hydroxychloroquine registered under CAS number 86-47-5. With the molecular formula C10H6ClNO3, it has a molar mass of 223.61 g/mol. The IUPAC name is 7-chloro-4-oxo-1H-quinoline-3-carboxylic acid. It is also known as 7-Chloro-4-hydroxy-3-quinolinecarboxylic acid or Quinoline, 3-carboxy-4-hydroxy-7-chloro-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Hydroxychloroquine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 7-Chloro-4-hydroxyquinoline-3-carboxylic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Hydroxychloroquine

View every impurity, metabolite and intermediate we list for Hydroxychloroquine.

Hydroxychloroquine impurities

Specifications & identifiers

Chemical identifiers
Product name	7-Chloro-4-hydroxyquinoline-3-carboxylic acid
Catalogue No.	VQ-037604
CAS Number	86-47-5
IUPAC name	7-chloro-4-oxo-1H-quinoline-3-carboxylic acid
Molecular formula	C₁₀H₆ClNO₃
Molecular weight	223.61 g/mol
Exact mass	223.0036
Grade	Reference Standard
HSN code	38229090
InChIKey	SACLIBNEKWTDEG-UHFFFAOYSA-N
SMILES	C1=CC2=C(C=C1Cl)NC=C(C2=O)C(=O)O
PubChem CID	66579

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	2 / 4
TPSA	66.4 Å²
Synonyms	7-Chloro-4-hydroxy-3-quinolinecarboxylic acid, 3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, Quinoline, 3-carboxy-4-hydroxy-7-chloro-, 3-Carboxy-4-hydroxy-7-chloroquinoline, 7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, 4-Hydroxy-7-chloroquinoline-3-carboxylic acid, usafkf-16, 7-Chloro-4-Hydroxylquinoline-3, 3-Quinolinecarboxylic acid, 7-chloro-1,4-dihydro-4-oxo-, 7-Chloro-4-Hydroxy-3-Carboxyquineoline

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 7-Chloro-4-hydroxyquinoline-3-carboxylic acid?

The CAS Registry Number of 7-Chloro-4-hydroxyquinoline-3-carboxylic acid is 86-47-5. It is also known as 7-Chloro-4-hydroxy-3-quinolinecarboxylic acid, 3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, Quinoline, 3-carboxy-4-hydroxy-7-chloro-.

What is the molecular formula and molecular weight of 7-Chloro-4-hydroxyquinoline-3-carboxylic acid?

7-Chloro-4-hydroxyquinoline-3-carboxylic acid has the molecular formula C10H6ClNO3 and a molecular weight of 223.61 g/mol. Its IUPAC name is 7-chloro-4-oxo-1H-quinoline-3-carboxylic acid.

What is 7-Chloro-4-hydroxyquinoline-3-carboxylic acid used for?

7-Chloro-4-hydroxyquinoline-3-carboxylic acid is supplied as a characterised reference material related to Hydroxychloroquine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 7-Chloro-4-hydroxyquinoline-3-carboxylic acid can I order?

We supply 7-Chloro-4-hydroxyquinoline-3-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 7-Chloro-4-hydroxyquinoline-3-carboxylic acid?

Yes. Every lot of 7-Chloro-4-hydroxyquinoline-3-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 7-Chloro-4-hydroxyquinoline-3-carboxylic acid be shipped internationally?

Yes. 7-Chloro-4-hydroxyquinoline-3-carboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.