7-Chloroquinolin-4(1H)-one

Name: 7-Chloroquinolin-4(1H)-one
Brand: Vaqora Chemicals
SKU: VQ-027514

About 7-Chloroquinolin-4(1H)-one

7-Chloroquinolin-4(1H)-one is a metabolite or degradation product of Piperaquine carrying the CAS registry number 86-99-7. Formula C9H6ClNO, molecular weight 179.6 g/mol. The IUPAC name is 7-chloro-1H-quinolin-4-one. It is also known as 7-Chloro-4-hydroxyquinoline or 4-Quinolinol, 7-chloro-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Piperaquine, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 7-Chloroquinolin-4(1H)-one in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Piperaquine

View every impurity, metabolite and intermediate we list for Piperaquine.

Piperaquine impurities

Specifications & identifiers

Chemical identifiers
Product name	7-Chloroquinolin-4(1H)-one
Catalogue No.	VQ-027514
CAS Number	86-99-7
IUPAC name	7-chloro-1H-quinolin-4-one
Molecular formula	C₉H₆ClNO
Molecular weight	179.6 g/mol
Exact mass	179.0138
Grade	Reference Standard
HSN code	38229090
InChIKey	XMFXTXKSWIDMER-UHFFFAOYSA-N
SMILES	C1=CC2=C(C=C1Cl)NC=CC2=O
PubChem CID	66593

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	1 / 2
TPSA	29.1 Å²
Synonyms	7-Chloro-4-hydroxyquinoline, 4-Quinolinol, 7-chloro-, 7-Chloroquinolin-4-ol, 7-Chloro-4-quinolinol, 4(1H)-Quinolinone, 7-chloro-, chloroxoquinoline, 7-chloro-4(1H)-quinolinone, 7-chloro-quinolin-4-ol, 7-Chloro-4(1H)-quinolone, 4mrw, 7-Chloro4-quinolinol, 7-Chloro-4-keto-quinoline

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 7-Chloroquinolin-4(1H)-one?

The CAS Registry Number of 7-Chloroquinolin-4(1H)-one is 86-99-7. It is also known as 7-Chloro-4-hydroxyquinoline, 4-Quinolinol, 7-chloro-, 7-Chloroquinolin-4-ol.

What is the molecular formula and molecular weight of 7-Chloroquinolin-4(1H)-one?

7-Chloroquinolin-4(1H)-one has the molecular formula C9H6ClNO and a molecular weight of 179.6 g/mol. Its IUPAC name is 7-chloro-1H-quinolin-4-one.

What is 7-Chloroquinolin-4(1H)-one used for?

7-Chloroquinolin-4(1H)-one is supplied as a characterised reference material related to Piperaquine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 7-Chloroquinolin-4(1H)-one can I order?

We supply 7-Chloroquinolin-4(1H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 7-Chloroquinolin-4(1H)-one?

Yes. Every lot of 7-Chloroquinolin-4(1H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 7-Chloroquinolin-4(1H)-one be shipped internationally?

Yes. 7-Chloroquinolin-4(1H)-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.