7-Hydroxy Quetiapine

Name: 7-Hydroxy Quetiapine
Brand: Vaqora Chemicals
SKU: VQ-027690

About 7-Hydroxy Quetiapine

7-Hydroxy Quetiapine (CAS 139079-39-3) is a metabolite or degradation product of Quetiapine offered by Vaqora Chemicals. With the molecular formula C21H25N3O3S, it has a molar mass of 399.5 g/mol. Its systematic (IUPAC) name is 6-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]benzo[b][1,4]benzothiazepin-2-ol. It is also known as 7-Hydroxy Quetiapine HCl.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Quetiapine, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 7-Hydroxy Quetiapine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Quetiapine

View every impurity, metabolite and intermediate we list for Quetiapine.

Quetiapine impurities

Specifications & identifiers

Chemical identifiers
Product name	7-Hydroxy Quetiapine
Catalogue No.	VQ-027690
CAS Number	139079-39-3
IUPAC name	6-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]benzo[b][1,4]benzothiazepin-2-ol
Molecular formula	C₂₁H₂₅N₃O₃S
Molecular weight	399.5 g/mol
Exact mass	399.1617
Grade	Reference Standard
HSN code	38229090
InChIKey	VEGVCHRFYPFJFO-UHFFFAOYSA-N
SMILES	C1CN(CCN1CCOCCO)C2=NC3=C(C=C(C=C3)O)SC4=CC=CC=C42
PubChem CID	132203

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	2 / 6
TPSA	93.8 Å²
Synonyms	Dibenzo[b,f][1,4]thiazepin-7-ol, 11-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]-, Dibenzo(b,f)(1,4)thiazepin-7-ol, 11-(4-(2-(2-hydroxyethoxy)ethyl)-1-piperazinyl)-, 7-Hydroxy Quetiapine HCl, Dibenzo[b,f][1,4]thiazepin-7-ol,11-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]-, 11-(4-(2-(2-Hydroxyethoxy)ethyl)-1-piperazinyl)dibenzo(b,f)(1,4)thiazepin-7-ol, 11-[4-[2-(2-Hydroxyethoxy)ethyl]-1-piperazinyl]-dibenzo[b,f][1,4]thiazepin-7-ol, 11-{4-[2-(2-Hydroxy-ethoxy)-ethyl]-piperazin-1-yl}-dibenzo[b,f][1,4]thiazepin-7-ol, 11-{4-[2-(2-Hydroxyethoxy)ethyl]piperazin-1-yl}dibenzo[b,f][1,4]thiazepin-7-ol, 2-(2-(7-Hydroxy-4-dibenzo(b,f)(1,4)thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H400Very toxic to aquatic life

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 7-Hydroxy Quetiapine?

The CAS Registry Number of 7-Hydroxy Quetiapine is 139079-39-3. It is also known as Dibenzo[b,f][1,4]thiazepin-7-ol, 11-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]-, Dibenzo(b,f)(1,4)thiazepin-7-ol, 11-(4-(2-(2-hydroxyethoxy)ethyl)-1-piperazinyl)-, 7-Hydroxy Quetiapine HCl.

What is the molecular formula and molecular weight of 7-Hydroxy Quetiapine?

7-Hydroxy Quetiapine has the molecular formula C21H25N3O3S and a molecular weight of 399.5 g/mol. Its IUPAC name is 6-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]benzo[b][1,4]benzothiazepin-2-ol.

What is 7-Hydroxy Quetiapine used for?

7-Hydroxy Quetiapine is supplied as a characterised reference material related to Quetiapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 7-Hydroxy Quetiapine can I order?

We supply 7-Hydroxy Quetiapine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 7-Hydroxy Quetiapine?

Yes. Every lot of 7-Hydroxy Quetiapine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 7-Hydroxy Quetiapine be shipped internationally?

Yes. 7-Hydroxy Quetiapine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.