7-Methylindoline-2,3-dione

Name: 7-Methylindoline-2,3-dione
Brand: Vaqora Chemicals
SKU: VQ-032670

About 7-Methylindoline-2,3-dione

Vaqora Chemicals supplies 7-Methylindoline-2,3-dione, an impurity of Suvorexant registered under CAS number 1127-59-9. The compound has the formula C9H7NO2, corresponding to a molecular weight of 161.16 g/mol. Its systematic (IUPAC) name is 7-methyl-1H-indole-2,3-dione. Common synonyms include 7-Methylisatin and 1H-Indole-2,3-dione, 7-methyl-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Suvorexant, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 7-Methylindoline-2,3-dione is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Suvorexant

View every impurity, metabolite and intermediate we list for Suvorexant.

Suvorexant impurities

Specifications & identifiers

Chemical identifiers
Product name	7-Methylindoline-2,3-dione
Catalogue No.	VQ-032670
CAS Number	1127-59-9
IUPAC name	7-methyl-1H-indole-2,3-dione
Molecular formula	C₉H₇NO₂
Molecular weight	161.16 g/mol
Exact mass	161.0477
Grade	Reference Standard
HSN code	38229090
InChIKey	UEHZKEABUOAZSH-UHFFFAOYSA-N
SMILES	CC1=C2C(=CC=C1)C(=O)C(=O)N2
PubChem CID	14313

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	1 / 2
TPSA	46.2 Å²
Synonyms	7-Methylisatin, 1H-Indole-2,3-dione, 7-methyl-, 7-Methyl-2,3-indolinedione, 7-Methyl-indole-2,3-dione, 1H-Indole-2,3-dione, 7-methyl-(9CI), 7-methyl-2,3-dihydro-1H-indole-2,3-dione, Isatin-based compound, 41, 1H-Indole-2, 7-methyl-, 7-methyl-1H-indol-2,3-dione, 7-methyl-1~{H}-indole-2,3-dione, 7-methyl-1H-benzo[d]azolidine-2,3-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 7-Methylindoline-2,3-dione?

The CAS Registry Number of 7-Methylindoline-2,3-dione is 1127-59-9. It is also known as 7-Methylisatin, 1H-Indole-2,3-dione, 7-methyl-, 7-Methyl-2,3-indolinedione.

What is the molecular formula and molecular weight of 7-Methylindoline-2,3-dione?

7-Methylindoline-2,3-dione has the molecular formula C9H7NO2 and a molecular weight of 161.16 g/mol. Its IUPAC name is 7-methyl-1H-indole-2,3-dione.

What is 7-Methylindoline-2,3-dione used for?

7-Methylindoline-2,3-dione is supplied as a characterised reference material related to Suvorexant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 7-Methylindoline-2,3-dione can I order?

We supply 7-Methylindoline-2,3-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 7-Methylindoline-2,3-dione?

Yes. Every lot of 7-Methylindoline-2,3-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 7-Methylindoline-2,3-dione be shipped internationally?

Yes. 7-Methylindoline-2,3-dione is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.