8-Demethyl Ivabradine

Name: 8-Demethyl Ivabradine
Brand: Vaqora Chemicals
SKU: VQ-031326

About 8-Demethyl Ivabradine

8-Demethyl Ivabradine (CAS 304464-97-9) is a metabolite or degradation product of Ivabradine offered by Vaqora Chemicals. The compound has the formula C26H34N2O5, corresponding to a molecular weight of 454.6 g/mol. It is also known as 8-Demethyl Ivabradine (Free Base) or 8-o-Desmethyl ivabradine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Ivabradine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 8-Demethyl Ivabradine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ivabradine

View every impurity, metabolite and intermediate we list for Ivabradine.

Ivabradine impurities

Specifications & identifiers

Chemical identifiers
Product name	8-Demethyl Ivabradine
Catalogue No.	VQ-031326
CAS Number	304464-97-9
IUPAC name	3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7-hydroxy-8-methoxy-2,5-dihydro-1H-3-benzazepin-4-one
Molecular formula	C₂₆H₃₄N₂O₅
Molecular weight	454.6 g/mol
Exact mass	454.2468
Grade	Reference Standard
HSN code	38229090
InChIKey	BMPIAMMIUINAOW-HXUWFJFHSA-N
SMILES	CN(CCCN1CCC2=CC(=C(C=C2CC1=O)O)OC)C[C@H]3CC4=CC(=C(C=C34)OC)OC
PubChem CID	71315777

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 6
TPSA	71.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 8-Demethyl Ivabradine?

The CAS Registry Number of 8-Demethyl Ivabradine is 304464-97-9. It is also known as 8-Demethyl Ivabradine (Free Base), 8-o-Desmethyl ivabradine.

What is the molecular formula and molecular weight of 8-Demethyl Ivabradine?

8-Demethyl Ivabradine has the molecular formula C26H34N2O5 and a molecular weight of 454.6 g/mol. Its IUPAC name is 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7-hydroxy-8-methoxy-2,5-dihydro-1H-3-benzazepin-4-one.

What is 8-Demethyl Ivabradine used for?

8-Demethyl Ivabradine is supplied as a characterised reference material related to Ivabradine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 8-Demethyl Ivabradine can I order?

We supply 8-Demethyl Ivabradine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 8-Demethyl Ivabradine?

Yes. Every lot of 8-Demethyl Ivabradine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 8-Demethyl Ivabradine be shipped internationally?

Yes. We export 8-Demethyl Ivabradine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.