9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn… 114488-14-1

Name: 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione
Brand: Vaqora Chemicals
SKU: VQ-035055

About 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione

9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione (CAS 114488-14-1) is an impurity of Betamethasone offered by Vaqora Chemicals. Formula C22H30O5, molecular weight 374.5 g/mol. It is also known as 1,2 Dihydro Beta Methyl Epoxide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Betamethasone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Betamethasone

View every impurity, metabolite and intermediate we list for Betamethasone.

Betamethasone impurities

Specifications & identifiers

Chemical identifiers
Product name	9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione
Catalogue No.	VQ-035055
CAS Number	114488-14-1
IUPAC name	(1S,2S,10S,11S,13S,14R,15S,17S)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-en-5-one
Molecular formula	C₂₂H₃₀O₅
Molecular weight	374.5 g/mol
Exact mass	374.2093
Grade	Reference Standard
HSN code	38229090
InChIKey	TUIYCBORCUOUBA-DEGNENOVSA-N
SMILES	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@]4([C@]35[C@@H](O5)C[C@@]2([C@]1(C(=O)CO)O)C)C
PubChem CID	88360198

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	2 / 5
TPSA	87.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione?

The CAS Registry Number of 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione is 114488-14-1. It is also known as 1,2 Dihydro Beta Methyl Epoxide, 9beta,11beta-Epoxy-17,21-dihydroxy-16beta-methyl-pregn-4-ene-3,20-dione.

What is the molecular formula and molecular weight of 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione?

9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione has the molecular formula C22H30O5 and a molecular weight of 374.5 g/mol. Its IUPAC name is (1S,2S,10S,11S,13S,14R,15S,17S)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-en-5-one.

What is 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione used for?

9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione is supplied as a characterised reference material related to Betamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione can I order?

We supply 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione?

Yes. Every lot of 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione be shipped internationally?

Yes. We export 9β,11β-Epoxy-17,21-dihydroxy-16β-methyl-pregn-4-ene-3,20-dione worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.