Abemaciclib Nitroso Impurity 1

Name: Abemaciclib Nitroso Impurity 1
Brand: Vaqora Chemicals
SKU: VQ-006802

About Abemaciclib Nitroso Impurity 1

Abemaciclib Nitroso Impurity 1 is a nitrosamine impurity of Abemaciclib from the Vaqora Chemicals catalogue at a purity of 96.04%. The compound has the formula C10H15N5O, corresponding to a molecular weight of 221.26 g/mol. The IUPAC name is 5-[(4-nitrosopiperazin-1-yl)methyl]pyridin-2-amine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Abemaciclib Nitroso Impurity 1 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Abemaciclib

View every impurity, metabolite and intermediate we list for Abemaciclib.

Abemaciclib impurities

Specifications & identifiers

Chemical identifiers
Product name	Abemaciclib Nitroso Impurity 1
Catalogue No.	VQ-006802
IUPAC name	5-[(4-nitrosopiperazin-1-yl)methyl]pyridin-2-amine
Molecular formula	C₁₀H₁₅N₅O
Molecular weight	221.26 g/mol
Exact mass	221.1277
Grade	Reference Standard
Purity / assay	96.04%
HSN code	38229090
InChIKey	ACFHOMXHTZMYKZ-UHFFFAOYSA-N
SMILES	C1CN(CCN1CC2=CN=C(C=C2)N)N=O
PubChem CID	178877144

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	1 / 6
TPSA	74.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the molecular formula and molecular weight of Abemaciclib Nitroso Impurity 1?

Abemaciclib Nitroso Impurity 1 has the molecular formula C10H15N5O and a molecular weight of 221.26 g/mol. Its IUPAC name is 5-[(4-nitrosopiperazin-1-yl)methyl]pyridin-2-amine.

What is Abemaciclib Nitroso Impurity 1 used for?

Abemaciclib Nitroso Impurity 1 is supplied as a characterised reference material related to Abemaciclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Abemaciclib Nitroso Impurity 1 can I order?

We supply Abemaciclib Nitroso Impurity 1 in Reference Standard (96.04%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Abemaciclib Nitroso Impurity 1?

Yes. Every lot of Abemaciclib Nitroso Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Abemaciclib Nitroso Impurity 1 be shipped internationally?

Yes. We export Abemaciclib Nitroso Impurity 1 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.