Abexinostat (PCI-24781)

Name: Abexinostat (PCI-24781)
Brand: Vaqora Chemicals
SKU: VQ-047304

About Abexinostat (PCI-24781)

Vaqora Chemicals supplies Abexinostat (PCI-24781), an API reference standard registered under CAS number 783355-60-2. With the molecular formula C21H23N3O5, it has a molar mass of 397.4 g/mol. The IUPAC name is 3-[(dimethylamino)methyl]-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide. Alternative names: Abexinostat and HDAC Inhibitor PCI-24781.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this the parent drug substance standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Abexinostat (PCI-24781) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Specifications & identifiers

Chemical identifiers
Product name	Abexinostat (PCI-24781)
Catalogue No.	VQ-047304
CAS Number	783355-60-2
IUPAC name	3-[(dimethylamino)methyl]-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide
Molecular formula	C₂₁H₂₃N₃O₅
Molecular weight	397.4 g/mol
Exact mass	397.1638
Grade	Reference Standard
HSN code	38229090
InChIKey	MAUCONCHVWBMHK-UHFFFAOYSA-N
SMILES	CN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO
PubChem CID	11749858

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	3 / 6
TPSA	104 Å²
Synonyms	Abexinostat, HDAC Inhibitor PCI-24781, 3-((dimethylamino)methyl)-N-(2-(4-(hydroxycarbamoyl)phenoxy)ethyl)benzofuran-2-carboxamide, PCI-24781 (Abexinostat), Abexinostat (USAN), 3-[(dimethylamino)methyl]-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]benzofuran-2-carboxamide, EX-A2123

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H311Toxic in contact with skin
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P262, P264, P264 + P265, P270, P273, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P318, P319, P321, P330, P361 + P364, P363, P391, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Abexinostat (PCI-24781)?

The CAS Registry Number of Abexinostat (PCI-24781) is 783355-60-2. It is also known as Abexinostat, HDAC Inhibitor PCI-24781, 3-((dimethylamino)methyl)-N-(2-(4-(hydroxycarbamoyl)phenoxy)ethyl)benzofuran-2-carboxamide.

What is the molecular formula and molecular weight of Abexinostat (PCI-24781)?

Abexinostat (PCI-24781) has the molecular formula C21H23N3O5 and a molecular weight of 397.4 g/mol. Its IUPAC name is 3-[(dimethylamino)methyl]-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide.

Which grade and pack sizes of Abexinostat (PCI-24781) can I order?

We supply Abexinostat (PCI-24781) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Abexinostat (PCI-24781)?

Yes. Every lot of Abexinostat (PCI-24781) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Abexinostat (PCI-24781) be shipped internationally?

Yes. Abexinostat (PCI-24781) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.