Acalabrutanib Impurity 11 (Cyclised Isomer) 2490433-97-9

Name: Acalabrutanib Impurity 11 (Cyclised Isomer)
Brand: Vaqora Chemicals
SKU: VQ-004331

About Acalabrutanib Impurity 11 (Cyclised Isomer)

Acalabrutanib Impurity 11 (Cyclised Isomer) is an impurity of Acalabrutinib carrying the CAS registry number 2490433-97-9. With the molecular formula C30H25N7O3, it has a molar mass of 531.6 g/mol. Common synonyms include Acalabrutinib (Unknown) RRT-2.01 and Acalabrutinib Impurity 11.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Acalabrutinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Acalabrutanib Impurity 11 (Cyclised Isomer) is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Acalabrutinib

View every impurity, metabolite and intermediate we list for Acalabrutinib.

Acalabrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Acalabrutanib Impurity 11 (Cyclised Isomer)
Catalogue No.	VQ-004331
CAS Number	2490433-97-9
IUPAC name	4-[5-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]-10-methyl-12-oxo-4,6,9,13-tetrazatricyclo[7.4.0.02,6]trideca-1(13),2,4,7,10-pentaen-3-yl]-N-pyridin-2-ylbenzamide
Molecular formula	C₃₀H₂₅N₇O₃
Molecular weight	531.6 g/mol
Exact mass	531.2019
Grade	Reference Standard
HSN code	38229090
InChIKey	DBIHVGGBNOQUGX-QFIPXVFZSA-N
SMILES	CC#CC(=O)N1CCC[C@H]1C2=NC(=C3N2C=CN4C3=NC(=O)C=C4C)C5=CC=C(C=C5)C(=O)NC6=CC=CC=N6
PubChem CID	164771821

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	1 / 5
TPSA	113 Å²
Synonyms	Acalabrutinib (Unknown) RRT-2.01, Acalabrutinib Impurity 11, Acalabrutinib ( Unknown) RRT-2.01 / Acalabrutinib Impurity 11, Acalabrutinib Impurity-11, Acalabrutinib ( Unknown) RRT-2.01 (as per alembic)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acalabrutanib Impurity 11 (Cyclised Isomer)?

The CAS Registry Number of Acalabrutanib Impurity 11 (Cyclised Isomer) is 2490433-97-9. It is also known as Acalabrutinib (Unknown) RRT-2.01, Acalabrutinib Impurity 11, Acalabrutinib ( Unknown) RRT-2.01 / Acalabrutinib Impurity 11.

What is the molecular formula and molecular weight of Acalabrutanib Impurity 11 (Cyclised Isomer)?

Acalabrutanib Impurity 11 (Cyclised Isomer) has the molecular formula C30H25N7O3 and a molecular weight of 531.6 g/mol. Its IUPAC name is 4-[5-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]-10-methyl-12-oxo-4,6,9,13-tetrazatricyclo[7.4.0.02,6]trideca-1(13),2,4,7,10-pentaen-3-yl]-N-pyridin-2-ylbenzamide.

What is Acalabrutanib Impurity 11 (Cyclised Isomer) used for?

Acalabrutanib Impurity 11 (Cyclised Isomer) is supplied as a characterised reference material related to Acalabrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acalabrutanib Impurity 11 (Cyclised Isomer) can I order?

We supply Acalabrutanib Impurity 11 (Cyclised Isomer) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acalabrutanib Impurity 11 (Cyclised Isomer)?

Yes. Every lot of Acalabrutanib Impurity 11 (Cyclised Isomer) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acalabrutanib Impurity 11 (Cyclised Isomer) be shipped internationally?

Yes. We export Acalabrutanib Impurity 11 (Cyclised Isomer) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.