Acalabrutinib R-Isomer

Name: Acalabrutinib R-Isomer
Brand: Vaqora Chemicals
SKU: VQ-004340

About Acalabrutinib R-Isomer

Vaqora Chemicals supplies Acalabrutinib R-Isomer, an impurity of Acalabrutinib registered under CAS number 1952316-43-6 at a purity of 98%. With the molecular formula C26H23N7O2, it has a molar mass of 465.5 g/mol. Systematically, it is named 4-[8-amino-3-[(2R)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide. Common synonyms include Acalabrutinib enantiomer and (R)-Acalabrutinib.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Acalabrutinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Acalabrutinib R-Isomer in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Acalabrutinib

View every impurity, metabolite and intermediate we list for Acalabrutinib.

Acalabrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Acalabrutinib R-Isomer
Catalogue No.	VQ-004340
CAS Number	1952316-43-6
IUPAC name	4-[8-amino-3-[(2R)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide
Molecular formula	C₂₆H₂₃N₇O₂
Molecular weight	465.5 g/mol
Exact mass	465.1913
Grade	Reference Standard
Purity / assay	98%
HSN code	38229090
InChIKey	WDENQIQQYWYTPO-LJQANCHMSA-N
SMILES	CC#CC(=O)N1CCC[C@@H]1C2=NC(=C3N2C=CN=C3N)C4=CC=C(C=C4)C(=O)NC5=CC=CC=N5
PubChem CID	121413436

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 6
TPSA	119 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acalabrutinib R-Isomer?

The CAS Registry Number of Acalabrutinib R-Isomer is 1952316-43-6. It is also known as Acalabrutinib enantiomer, (R)-Acalabrutinib, Acalabrutinib, (R)-.

What is the molecular formula and molecular weight of Acalabrutinib R-Isomer?

Acalabrutinib R-Isomer has the molecular formula C26H23N7O2 and a molecular weight of 465.5 g/mol. Its IUPAC name is 4-[8-amino-3-[(2R)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide.

What is Acalabrutinib R-Isomer used for?

Acalabrutinib R-Isomer is supplied as a characterised reference material related to Acalabrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acalabrutinib R-Isomer can I order?

We supply Acalabrutinib R-Isomer in Reference Standard (98%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acalabrutinib R-Isomer?

Yes. Every lot of Acalabrutinib R-Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acalabrutinib R-Isomer be shipped internationally?

Yes. We export Acalabrutinib R-Isomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.