Acoramidis

Name: Acoramidis
Brand: Vaqora Chemicals
SKU: VQ-007291

About Acoramidis

Vaqora Chemicals supplies Acoramidis, a high-purity reference standard of Acoramidis registered under CAS number 1446711-81-4. Its molecular formula is C15H17FN2O3 and its molecular weight is 292.3 g/mol. Its systematic (IUPAC) name is 3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid. Common synonyms include AG-10 and AG10.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Acoramidis, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Acoramidis in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Acoramidis

View every impurity, metabolite and intermediate we list for Acoramidis.

Acoramidis impurities

Specifications & identifiers

Chemical identifiers
Product name	Acoramidis
Catalogue No.	VQ-007291
CAS Number	1446711-81-4
Other CAS	2242751-53-5
IUPAC name	3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid
Molecular formula	C₁₅H₁₇FN₂O₃
Molecular weight	292.3 g/mol
Exact mass	292.1223
Grade	Reference Standard
HSN code	38229090
InChIKey	WBFUHHBPNXWNCC-UHFFFAOYSA-N
SMILES	CC1=C(C(=NN1)C)CCCOC2=C(C=CC(=C2)C(=O)O)F
PubChem CID	71464713

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 5
TPSA	75.2 Å²
Synonyms	3-(3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy)-4-fluorobenzoic acid, AG-10, AG10, Benzoic acid, 3-(3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy)-4-fluoro-, TTR Stabilizer AG10, Transthyretin Stabilizer AG10, 4hiq, Acoramidis (USAN), 3-[3-(3,5-Dimethyl-4-pyrazolyl)propoxy]-4-fluorobenzoic Acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acoramidis?

The CAS Registry Number of Acoramidis is 1446711-81-4. It is also known as 3-(3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy)-4-fluorobenzoic acid, AG-10, AG10.

What is the molecular formula and molecular weight of Acoramidis?

Acoramidis has the molecular formula C15H17FN2O3 and a molecular weight of 292.3 g/mol. Its IUPAC name is 3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid.

What is Acoramidis used for?

Acoramidis is supplied as a characterised reference material related to Acoramidis. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acoramidis can I order?

We supply Acoramidis in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acoramidis?

Yes. Every lot of Acoramidis is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acoramidis be shipped internationally?

Yes. Acoramidis is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.