Adapalene
Synonyms: 6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid · 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid · 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthalenecarboxylic acid · 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid
Adapalene (CAS 106685-40-9) – Adapalene reference standard. C28H28O3, MW 412.5. Get a quote from Vaqora Chemicals, COA included, shipped worldwide.
About Adapalene
Listed under CAS 106685-40-9, Adapalene is a high-purity reference standard of Adapalene available from Vaqora Chemicals. With the molecular formula C28H28O3, it has a molar mass of 412.5 g/mol. The IUPAC name is 6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid. Common synonyms include Differin and Differin Gel.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.
Laboratories use this Adapalene standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Adapalene is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.
Typical applications
- Identification & assay
- Method development & validation
- QC reference material
Industries
View every impurity, metabolite and intermediate we list for Adapalene.
Adapalene impuritiesSpecifications & identifiers
| Product name | Adapalene |
|---|---|
| Catalogue No. | VQ-007306 |
| CAS Number | 106685-40-9 |
| IUPAC name | 6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid |
| Molecular formula | C28H28O3 |
| Molecular weight | 412.5 g/mol |
| Exact mass | 412.2038 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | LZCDAPDGXCYOEH-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5 |
| PubChem CID | 60164 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 7.7 |
| H-bond donors / acceptors | 1 / 3 |
| TPSA | 46.5 Ų |
| Synonyms | 6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid, 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid, 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthalenecarboxylic acid, 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid, Differin, Differin Gel, Adaferin, CD-271, Differine, CD 271, 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid, 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H302Harmful if swallowedH315Causes skin irritationH317May cause an allergic skin reactionH319Causes serious eye irritationH335May cause respiratory irritationH361Suspected of damaging fertility or the unborn child
Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Adapalene?
The CAS Registry Number of Adapalene is 106685-40-9. It is also known as 6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid, 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid, 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthalenecarboxylic acid.
What is the molecular formula and molecular weight of Adapalene?
Adapalene has the molecular formula C28H28O3 and a molecular weight of 412.5 g/mol. Its IUPAC name is 6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid.
What is Adapalene used for?
Adapalene is supplied as a characterised reference material related to Adapalene. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Adapalene can I order?
We supply Adapalene in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Adapalene?
Yes. Every lot of Adapalene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Adapalene be shipped internationally?
Yes. Adapalene is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Adapalene
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