Adefovir Dipivoxil

Name: Adefovir Dipivoxil
Brand: Vaqora Chemicals
SKU: VQ-020743

About Adefovir Dipivoxil

Adefovir Dipivoxil (CAS 142340-99-6) is an impurity of Adefovir offered by Vaqora Chemicals. Its molecular formula is C20H32N5O8P and its molecular weight is 501.5 g/mol. Common synonyms include Adefovir pivoxil and Adefovir di(pivaloyloxymethyl) ester.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Adefovir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Adefovir

View every impurity, metabolite and intermediate we list for Adefovir.

Adefovir impurities

Specifications & identifiers

Chemical identifiers
Product name	Adefovir Dipivoxil
Catalogue No.	VQ-020743
CAS Number	142340-99-6
IUPAC name	[2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate
Molecular formula	C₂₀H₃₂N₅O₈P
Molecular weight	501.5 g/mol
Exact mass	501.1988
Grade	Reference Standard
HSN code	38229090
InChIKey	WOZSCQDILHKSGG-UHFFFAOYSA-N
SMILES	CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C(N=CN=C21)N)OCOC(=O)C(C)(C)C
PubChem CID	60871

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	1 / 12
TPSA	167 Å²
Synonyms	Adefovir pivoxil, Adefovir di(pivaloyloxymethyl) ester, 9-(2-((Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine, 9-(2-((-Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine, adefovir depivoxil, bis-POM PMEA, Adefovir dipivoxyl, GS 840, GS-840, Adefovir pivoxil (JAN), Adefovir dipivoxil (USAN), 9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Adefovir Dipivoxil?

The CAS Registry Number of Adefovir Dipivoxil is 142340-99-6. It is also known as Adefovir pivoxil, Adefovir di(pivaloyloxymethyl) ester, 9-(2-((Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine.

What is the molecular formula and molecular weight of Adefovir Dipivoxil?

Adefovir Dipivoxil has the molecular formula C20H32N5O8P and a molecular weight of 501.5 g/mol. Its IUPAC name is [2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate.

What is Adefovir Dipivoxil used for?

Adefovir Dipivoxil is supplied as a characterised reference material related to Adefovir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Adefovir Dipivoxil can I order?

We supply Adefovir Dipivoxil in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Adefovir Dipivoxil?

Yes. Every lot of Adefovir Dipivoxil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Adefovir Dipivoxil be shipped internationally?

Yes. Adefovir Dipivoxil is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.