Afacifenacin

Name: Afacifenacin
Brand: Vaqora Chemicals
SKU: VQ-043519

About Afacifenacin

Afacifenacin is an API impurity reference standard carrying the CAS registry number 877606-63-8. Formula C27H26F3N3O2, molecular weight 481.5 g/mol. Its systematic (IUPAC) name is (4S)-4-phenyl-3-[1-[[3-(trifluoromethoxy)phenyl]methyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one. Alternative names: NS-986 and afacifenacine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This the parent drug substance impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Afacifenacin
Catalogue No.	VQ-043519
CAS Number	877606-63-8
IUPAC name	(4S)-4-phenyl-3-[1-[[3-(trifluoromethoxy)phenyl]methyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one
Molecular formula	C₂₇H₂₆F₃N₃O₂
Molecular weight	481.5 g/mol
Exact mass	481.1977
Grade	Reference Standard
HSN code	38229090
InChIKey	IJUMFEAYOMCXAQ-VWLOTQADSA-N
SMILES	C1CN(CCC1N2[C@H](C3=CC=CC=C3NC2=O)C4=CC=CC=C4)CC5=CC(=CC=C5)OC(F)(F)F
PubChem CID	42647276

Physical properties
Physical form	Solid
LogP (XLogP3)	5.6
H-bond donors / acceptors	1 / 6
TPSA	44.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Afacifenacin?

The CAS Registry Number of Afacifenacin is 877606-63-8. It is also known as NS-986, afacifenacine, Afacifenacin fumarate.

What is the molecular formula and molecular weight of Afacifenacin?

Afacifenacin has the molecular formula C27H26F3N3O2 and a molecular weight of 481.5 g/mol. Its IUPAC name is (4S)-4-phenyl-3-[1-[[3-(trifluoromethoxy)phenyl]methyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one.

Which grade and pack sizes of Afacifenacin can I order?

We supply Afacifenacin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Afacifenacin?

Yes. Every lot of Afacifenacin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Afacifenacin be shipped internationally?

Yes. We export Afacifenacin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.