Alectinib Impurity 1

Name: Alectinib Impurity 1
Brand: Vaqora Chemicals
SKU: VQ-004352

About Alectinib Impurity 1

Listed under CAS 1256584-80-1, Alectinib Impurity 1 is an impurity of Alectinib available from Vaqora Chemicals with a typical assay of 95.19%. Its molecular formula is C21H17IN2O and its molecular weight is 440.3 g/mol. Its systematic (IUPAC) name is 9-ethyl-8-iodo-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile. Common synonyms include Aletinib Impurity 13 and CS-M1357.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Alectinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Alectinib

View every impurity, metabolite and intermediate we list for Alectinib.

Alectinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Alectinib Impurity 1
Catalogue No.	VQ-004352
CAS Number	1256584-80-1
IUPAC name	9-ethyl-8-iodo-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
Molecular formula	C₂₁H₁₇IN₂O
Molecular weight	440.3 g/mol
Exact mass	440.0386
Grade	Reference Standard
Purity / assay	95.19%
HSN code	38229090
InChIKey	IQWNZLQAANHDSH-UHFFFAOYSA-N
SMILES	CCC1=CC2=C(C=C1I)C(C3=C(C2=O)C4=C(N3)C=C(C=C4)C#N)(C)C
PubChem CID	66834374

Physical properties
Physical form	Solid
LogP (XLogP3)	5.6
H-bond donors / acceptors	1 / 2
TPSA	56.7 Å²
Synonyms	9-Ethyl-6,11-dihydro-8-iodo-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile, 9-Ethyl-6,6-dimethyl-8-iodo-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, 9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, 5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-8-iodo-6,6-dimethyl-11-oxo-, Aletinib Impurity 13, CS-M1357, 9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbaz ole-3-carbonitrile, 9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile-11

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Alectinib Impurity 1?

The CAS Registry Number of Alectinib Impurity 1 is 1256584-80-1. It is also known as 9-Ethyl-6,11-dihydro-8-iodo-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile, 9-Ethyl-6,6-dimethyl-8-iodo-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, 9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile.

What is the molecular formula and molecular weight of Alectinib Impurity 1?

Alectinib Impurity 1 has the molecular formula C21H17IN2O and a molecular weight of 440.3 g/mol. Its IUPAC name is 9-ethyl-8-iodo-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile.

What is Alectinib Impurity 1 used for?

Alectinib Impurity 1 is supplied as a characterised reference material related to Alectinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Alectinib Impurity 1 can I order?

We supply Alectinib Impurity 1 in Reference Standard (95.19%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Alectinib Impurity 1?

Yes. Every lot of Alectinib Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Alectinib Impurity 1 be shipped internationally?

Yes. We export Alectinib Impurity 1 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.