All-trans-Anhydro Retinol

Name: All-trans-Anhydro Retinol
Brand: Vaqora Chemicals
SKU: VQ-028725

About All-trans-Anhydro Retinol

All-trans-Anhydro Retinol (CAS 1224-78-8) is an impurity of Retinol offered by Vaqora Chemicals. Formula C20H28, molecular weight 268.4 g/mol. Its systematic (IUPAC) name is (6E)-6-[(2E,4E,6E)-3,7-dimethylnona-2,4,6,8-tetraenylidene]-1,5,5-trimethylcyclohexene. It is also known as Anhydrovitamin A or Anhydro-retinol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Retinol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Retinol

View every impurity, metabolite and intermediate we list for Retinol.

Retinol impurities

Specifications & identifiers

Chemical identifiers
Product name	All-trans-Anhydro Retinol
Catalogue No.	VQ-028725
CAS Number	1224-78-8
IUPAC name	(6E)-6-[(2E,4E,6E)-3,7-dimethylnona-2,4,6,8-tetraenylidene]-1,5,5-trimethylcyclohexene
Molecular formula	C₂₀H₂₈
Molecular weight	268.4 g/mol
Exact mass	268.2191
Grade	Reference Standard
HSN code	38229090
InChIKey	FWNRILWHNGFAIN-OYUWDNMLSA-N
SMILES	CC\1=CCCC(/C1=C\C=C(/C)\C=C\C=C(/C)\C=C)(C)C
PubChem CID	5287678

Physical properties
Physical form	Solid
LogP (XLogP3)	6.9
H-bond donors / acceptors	0 / 0
TPSA	0 Å²
Synonyms	Anhydrovitamin A, Anhydro-retinol, trans-anhydrovitamin A, (6E)-6-[(2E,4E,6E)-3,7-Dimethyl-2,4,6,8-nonatetraen-1-ylidene]-1,5,5-trimethylcyclohexene, (6E)-6-((2E,4E,6E)-3,7-Dimethyl-2,4,6,8-nonatetraen-1-ylidene)-1,5,5-trimethylcyclohexene, Anhydroretinol, Cyclohexene, 6-(3,7-dimethyl-2,4,6,8-nonatetraenylidene)-1,5,5-trimethyl-, (all-E)-, all-trans-Anhydro Retinol (90per cent), (6E)-6-[(2E,4E,6E)-3,7-dimethylnona-2,4,6,8-tetraen-1-ylidene]-1,5,5-trimethylcyclohexene, (6E)-6-[(2E,4E,6E)-3,7-dimethylnona-2,4,6,8-tetraenylidene]-1,5,5-trimethyl-cyclohexene

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H361Suspected of damaging fertility or the unborn child
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P261, P264, P264 + P265, P270, P272, P273, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P318, P321, P330, P333 + P317, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of All-trans-Anhydro Retinol?

The CAS Registry Number of All-trans-Anhydro Retinol is 1224-78-8. It is also known as Anhydrovitamin A, Anhydro-retinol, trans-anhydrovitamin A.

What is the molecular formula and molecular weight of All-trans-Anhydro Retinol?

All-trans-Anhydro Retinol has the molecular formula C20H28 and a molecular weight of 268.4 g/mol. Its IUPAC name is (6E)-6-[(2E,4E,6E)-3,7-dimethylnona-2,4,6,8-tetraenylidene]-1,5,5-trimethylcyclohexene.

What is All-trans-Anhydro Retinol used for?

All-trans-Anhydro Retinol is supplied as a characterised reference material related to Retinol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of All-trans-Anhydro Retinol can I order?

We supply All-trans-Anhydro Retinol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with All-trans-Anhydro Retinol?

Yes. Every lot of All-trans-Anhydro Retinol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can All-trans-Anhydro Retinol be shipped internationally?

Yes. All-trans-Anhydro Retinol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.