Allopregnanolone

Name: Allopregnanolone
Brand: Vaqora Chemicals
SKU: VQ-033339

About Allopregnanolone

Listed under CAS 516-54-1, Allopregnanolone is an impurity of Progesterone available from Vaqora Chemicals. With the molecular formula C21H34O2, it has a molar mass of 318.5 g/mol. Common synonyms include Brexanolone and Allotetrahydroprogesterone.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Progesterone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Allopregnanolone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Progesterone

View every impurity, metabolite and intermediate we list for Progesterone.

Progesterone impurities

Specifications & identifiers

Chemical identifiers
Product name	Allopregnanolone
Catalogue No.	VQ-033339
CAS Number	516-54-1
IUPAC name	1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
Molecular formula	C₂₁H₃₄O₂
Molecular weight	318.5 g/mol
Exact mass	318.2559
Grade	Reference Standard
HSN code	38229090
InChIKey	AURFZBICLPNKBZ-SYBPFIFISA-N
SMILES	CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@H](C4)O)C)C
PubChem CID	92786

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²
Synonyms	Brexanolone, Allotetrahydroprogesterone, 3alpha-hydroxy-5alpha-pregnan-20-one, 3alpha,5alpha-THP, Allopregnan-3alpha-ol-20-one, 3alpha-OH DHP, 3alpha-Hydroxy-5alpha-dihydroprogesterone, DEA NO. 2400, Pregnan-20-one, 3-hydroxy-, (3-alpha,5-alpha)-, alpha-Hydroxy-5 alpha-pregnan-20-one, 3

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Allopregnanolone?

The CAS Registry Number of Allopregnanolone is 516-54-1. It is also known as Brexanolone, Allotetrahydroprogesterone, 3alpha-hydroxy-5alpha-pregnan-20-one.

What is the molecular formula and molecular weight of Allopregnanolone?

Allopregnanolone has the molecular formula C21H34O2 and a molecular weight of 318.5 g/mol. Its IUPAC name is 1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone.

What is Allopregnanolone used for?

Allopregnanolone is supplied as a characterised reference material related to Progesterone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Allopregnanolone can I order?

We supply Allopregnanolone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Allopregnanolone?

Yes. Every lot of Allopregnanolone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Allopregnanolone be shipped internationally?

Yes. We export Allopregnanolone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.