Amifostine

Name: Amifostine
Brand: Vaqora Chemicals
SKU: VQ-034953

About Amifostine

Listed under CAS 20537-88-6, Amifostine is a high-purity reference standard of Amifostine available from Vaqora Chemicals. The compound has the formula C5H15N2O3PS, corresponding to a molecular weight of 214.23 g/mol. Systematically, it is named 2-(3-aminopropylamino)ethylsulfanylphosphonic acid. Alternative names: Ethyol and Aminopropylaminoethyl thiophosphate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Amifostine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Amifostine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Amifostine

View every impurity, metabolite and intermediate we list for Amifostine.

Amifostine impurities

Specifications & identifiers

Chemical identifiers
Product name	Amifostine
Catalogue No.	VQ-034953
CAS Number	20537-88-6
IUPAC name	2-(3-aminopropylamino)ethylsulfanylphosphonic acid
Molecular formula	C₅H₁₅N₂O₃PS
Molecular weight	214.23 g/mol
Exact mass	214.0541
Grade	Reference Standard
HSN code	38229090
InChIKey	JKOQGQFVAUAYPM-UHFFFAOYSA-N
SMILES	C(CN)CNCCSP(=O)(O)O
PubChem CID	2141

Physical properties
Physical form	Solid
LogP (XLogP3)	-4.5
H-bond donors / acceptors	4 / 6
TPSA	121 Å²
Synonyms	Ethyol, Aminopropylaminoethyl thiophosphate, Ethiofos Anhydrous, Amifostine Anhydrous, S-(2-((3-Aminopropyl)amino)ethyl) dihydrogen phosphorothioate, ({2-[(3-aminopropyl)amino]ethyl}sulfanyl)phosphonic acid, Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), ((2-((3-aminopropyl)amino)ethyl)sulfanyl)phosphonic acid, S-[2-[(3-Aminopropyl)amino]ethyl] dihydrogen phosphorothioate, S-{2-[(3-Aminopropyl)amino]ethyl} dihydrogen phosphorothioate, Aminopropyl Aminoethylthiophosphate, Aminopropylaminoethylthiophosphoric Acid Trihydrate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amifostine?

The CAS Registry Number of Amifostine is 20537-88-6. It is also known as Ethyol, Aminopropylaminoethyl thiophosphate, Ethiofos Anhydrous.

What is the molecular formula and molecular weight of Amifostine?

Amifostine has the molecular formula C5H15N2O3PS and a molecular weight of 214.23 g/mol. Its IUPAC name is 2-(3-aminopropylamino)ethylsulfanylphosphonic acid.

What is Amifostine used for?

Amifostine is supplied as a characterised reference material related to Amifostine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amifostine can I order?

We supply Amifostine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amifostine?

Yes. Every lot of Amifostine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amifostine be shipped internationally?

Yes. Amifostine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.