Amitriptyline

Name: Amitriptyline
Brand: Vaqora Chemicals
SKU: VQ-038699

About Amitriptyline

Amitriptyline (CAS 50-48-6) is an impurity of Nortriptyline offered by Vaqora Chemicals. Formula C20H23N, molecular weight 277.4 g/mol. Systematically, it is named N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine. Alternative names: Amitriptylin and Damitriptyline.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 8 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Nortriptyline to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nortriptyline

View every impurity, metabolite and intermediate we list for Nortriptyline.

Nortriptyline impurities

Specifications & identifiers

Chemical identifiers
Product name	Amitriptyline
Catalogue No.	VQ-038699
CAS Number	50-48-6
IUPAC name	N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
Molecular formula	C₂₀H₂₃N
Molecular weight	277.4 g/mol
Exact mass	277.183
Grade	Reference Standard
HSN code	38229090
InChIKey	KRMDCWKBEZIMAB-UHFFFAOYSA-N
SMILES	CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31
PubChem CID	2160

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	0 / 1
TPSA	3.2 Å²
Synonyms	Amitriptylin, Damitriptyline, Triptanol, Flavyl, Proheptadiene, Triptisol, Amitryptiline, Tryptanol, Triptilin, Laroxyl, Amytriptylin, Amitryptyline

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301+H311+H331Toxic if swallowed, in contact with skin or if inhaled
H301Toxic if swallowed
H302Harmful if swallowed
H311Toxic in contact with skin
H318Causes serious eye damage
H331Toxic if inhaled
H361Suspected of damaging fertility or the unborn child
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P262, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P316, P317, P318, P321, P330, P361 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amitriptyline?

The CAS Registry Number of Amitriptyline is 50-48-6. It is also known as Amitriptylin, Damitriptyline, Triptanol.

What is the molecular formula and molecular weight of Amitriptyline?

Amitriptyline has the molecular formula C20H23N and a molecular weight of 277.4 g/mol. Its IUPAC name is N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine.

What is Amitriptyline used for?

Amitriptyline is supplied as a characterised reference material related to Nortriptyline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amitriptyline can I order?

We supply Amitriptyline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amitriptyline?

Yes. Every lot of Amitriptyline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amitriptyline be shipped internationally?

Yes. Amitriptyline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.