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Azelastine N-Oxide

Synonyms: Azelastine N-Oxide (Mixture of Diastereomers) · 4-((4-chlorophenyl)methyl)-2-(1-methyl-1-oxidoazepan-1-ium-4-yl)phthalazin-1-one · 4-(4-(4-Chlorobenzyl)-1-oxophthalazin-2(1H)-yl)-1-methylazepane 1-oxide · Azelastine N-oxide, mixture of diastereomers

CAS No.640279-88-5
FormulaC22H24ClN3O2
Mol. weight397.90
Catalogue No.VQ-021699
PurityReference Standard
HSN38229090

Azelastine N-Oxide (CAS 640279-88-5) – Azelastine impurity standard. C22H24ClN3O2, MW 397.9. Supplied by Vaqora Chemicals with COA, exported worldwide.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
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Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About Azelastine N-Oxide

Azelastine N-Oxide is a metabolite or degradation product of Azelastine carrying the CAS registry number 640279-88-5. Its molecular formula is C22H24ClN3O2 and its molecular weight is 397.9 g/mol. Its systematic (IUPAC) name is 4-[(4-chlorophenyl)methyl]-2-(1-methyl-1-oxidoazepan-1-ium-4-yl)phthalazin-1-one. It is also known as Azelastine N-Oxide (Mixture of Diastereomers) or Azelastine N-oxide, mixture of diastereomers.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Azelastine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Azelastine N-Oxide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling
  • Fine chemical synthesis

Industries

Related to Azelastine

View every impurity, metabolite and intermediate we list for Azelastine.

Azelastine impurities

Specifications & identifiers

Chemical identifiers
Product nameAzelastine N-Oxide
Catalogue No.VQ-021699
CAS Number640279-88-5
IUPAC name4-[(4-chlorophenyl)methyl]-2-(1-methyl-1-oxidoazepan-1-ium-4-yl)phthalazin-1-one
Molecular formulaC22H24ClN3O2
Molecular weight397.9 g/mol
Exact mass397.1557
GradeReference Standard
HSN code38229090
InChIKeyQFWLGALGCDUDAP-UHFFFAOYSA-N
SMILESC[N+]1(CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl)[O-]
PubChem CID71313553
Physical properties
Physical formSolid
LogP (XLogP3)3.8
H-bond donors / acceptors0 / 3
TPSA50.7 Ų
SynonymsAzelastine N-Oxide (Mixture of Diastereomers), 4-((4-chlorophenyl)methyl)-2-(1-methyl-1-oxidoazepan-1-ium-4-yl)phthalazin-1-one, 4-(4-(4-Chlorobenzyl)-1-oxophthalazin-2(1H)-yl)-1-methylazepane 1-oxide, Azelastine N-oxide, mixture of diastereomers, Azelastine-N-Oxide (Mixture of Diastereomers), 4-[(4-chlorophenyl)methyl]-2-(1-methyl-1-oxido-azepan-1-ium-4-yl)phthalazin-1-one, 4-[(4-Chlorophenyl)methyl]-2-(1-methyl-1-oxo-1lambda~5~-azepan-4-yl)phthalazin-1(2H)-one

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant
GHS08 Health hazard
Health hazard

Signal word: Danger

Hazard statements

  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P302 + P352, P317, P318, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Azelastine N-Oxide?

The CAS Registry Number of Azelastine N-Oxide is 640279-88-5. It is also known as Azelastine N-Oxide (Mixture of Diastereomers), 4-((4-chlorophenyl)methyl)-2-(1-methyl-1-oxidoazepan-1-ium-4-yl)phthalazin-1-one, 4-(4-(4-Chlorobenzyl)-1-oxophthalazin-2(1H)-yl)-1-methylazepane 1-oxide.

What is the molecular formula and molecular weight of Azelastine N-Oxide?

Azelastine N-Oxide has the molecular formula C22H24ClN3O2 and a molecular weight of 397.9 g/mol. Its IUPAC name is 4-[(4-chlorophenyl)methyl]-2-(1-methyl-1-oxidoazepan-1-ium-4-yl)phthalazin-1-one.

What is Azelastine N-Oxide used for?

Azelastine N-Oxide is supplied as a characterised reference material related to Azelastine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Azelastine N-Oxide can I order?

We supply Azelastine N-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Azelastine N-Oxide?

Yes. Every lot of Azelastine N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Azelastine N-Oxide be shipped internationally?

Yes. Azelastine N-Oxide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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